Do affective or dissociative symptoms mediate the association between childhood sexual trauma and transition to psychosis in an ultra-high risk cohort?

Research output: Contribution to journalArticle

Authors

  • Andrew Thompson
  • Barnaby Nelson
  • Patrick D McGorry
  • Alison R Yung
  • Ashleigh Lin

Colleges, School and Institutes

External organisations

  • Division of Mental Health and Wellbeing, Warwick Medical School, University of Warwick, UK. Electronic address: andrew.d.thompson@warwick.ac.uk.
  • Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, Australia; The Centre for Youth Mental Health, The University of Melbourne, Melbourne, Australia.
  • Department of Psychology, Peking University, Beijing, China ; School of Psychology, University of Birmingham, Birmingham, UK.
  • University of Manchester
  • Telethon Kids Institute, The University of Western Australia, Australia

Abstract

We have previously reported an association between childhood sexual trauma and transition to psychosis in an Ultra High Risk (UHR) population. We aimed to investigate if this association was mediated by affective or dissociative symptoms. Data were from a large UHR for psychosis cohort study. None of the potential mediators (depression, anxiety, dissociation, mood swings and mania, assessed by the HAM-D, HAM-A and the CAARMS symptom scales) significantly mediated the total association between sexual abuse scores and transition. At the point of transition, the mechanistic pathway from sexual trauma to psychosis does not appear to operate through affective symptoms.

Details

Original languageEnglish
Pages (from-to)182-185
Number of pages4
JournalPsychiatry Research
Volume236
Publication statusPublished - 28 Feb 2016

Keywords

  • Adolescent, Adult, Affective Symptoms/psychology, Anxiety/psychology, Bipolar Disorder/psychology, Child, Child Abuse, Sexual/psychology, Cohort Studies, Depression/psychology, Dissociative Disorders/psychology, Female, Humans, Male, Mood Disorders/psychology, Psychotic Disorders/psychology, Risk, Young Adult