Diverse Profiles of Anxiety Related Disorders in Fragile X, Cornelia de Lange and Rubinstein–Taybi Syndromes

Research output: Contribution to journalArticlepeer-review

Standard

Diverse Profiles of Anxiety Related Disorders in Fragile X, Cornelia de Lange and Rubinstein–Taybi Syndromes. / Crawford, Hayley; Waite, Jane; Oliver, Chris.

In: Journal of Autism and Developmental Disorders, Vol. 47, No. 12, 12.2017, p. 3728–3740.

Research output: Contribution to journalArticlepeer-review

Harvard

APA

Vancouver

Author

Bibtex

@article{99b5ca9ef42b4d27a5e55491bf31f6f3,
title = "Diverse Profiles of Anxiety Related Disorders in Fragile X, Cornelia de Lange and Rubinstein–Taybi Syndromes",
abstract = "Anxiety disorders are heightened in specific genetic syndromes in comparison to intellectual disability of heterogeneous aetiology. In this study, we described and contrasted anxiety symptomatology in fragile X (FXS), Cornelia de Lange (CdLS) and Rubinstein–Taybi syndromes (RTS), and compared the symptomatology to normative data for typically-developing children and children diagnosed with an anxiety disorder. Scores did not differ between children diagnosed with an anxiety disorder and (a) participants with FXS on social phobia, panic/agoraphobia, physical injury fears, and obsessive–compulsive subscales (b) participants with CdLS on separation anxiety, generalized anxiety, panic/agoraphobia, physical injury fears and obsessive–compulsive subscales, and (c) participants with RTS on panic/agoraphobia and obsessive–compulsive subscales. The results highlight divergent profiles of anxiety symptomatology between these groups.",
keywords = "Anxiety, Cornelia de Lange syndrome, Fragile X syndrome, Genetic syndromes, Intellectual disability, Rubinstein–Taybi syndrome",
author = "Hayley Crawford and Jane Waite and Chris Oliver",
year = "2017",
month = dec,
doi = "10.1007/s10803-016-3015-y",
language = "English",
volume = "47",
pages = "3728–3740",
journal = "Journal of Autism and Developmental Disorders",
issn = "0162-3257",
publisher = "Springer",
number = "12",

}

RIS

TY - JOUR

T1 - Diverse Profiles of Anxiety Related Disorders in Fragile X, Cornelia de Lange and Rubinstein–Taybi Syndromes

AU - Crawford, Hayley

AU - Waite, Jane

AU - Oliver, Chris

PY - 2017/12

Y1 - 2017/12

N2 - Anxiety disorders are heightened in specific genetic syndromes in comparison to intellectual disability of heterogeneous aetiology. In this study, we described and contrasted anxiety symptomatology in fragile X (FXS), Cornelia de Lange (CdLS) and Rubinstein–Taybi syndromes (RTS), and compared the symptomatology to normative data for typically-developing children and children diagnosed with an anxiety disorder. Scores did not differ between children diagnosed with an anxiety disorder and (a) participants with FXS on social phobia, panic/agoraphobia, physical injury fears, and obsessive–compulsive subscales (b) participants with CdLS on separation anxiety, generalized anxiety, panic/agoraphobia, physical injury fears and obsessive–compulsive subscales, and (c) participants with RTS on panic/agoraphobia and obsessive–compulsive subscales. The results highlight divergent profiles of anxiety symptomatology between these groups.

AB - Anxiety disorders are heightened in specific genetic syndromes in comparison to intellectual disability of heterogeneous aetiology. In this study, we described and contrasted anxiety symptomatology in fragile X (FXS), Cornelia de Lange (CdLS) and Rubinstein–Taybi syndromes (RTS), and compared the symptomatology to normative data for typically-developing children and children diagnosed with an anxiety disorder. Scores did not differ between children diagnosed with an anxiety disorder and (a) participants with FXS on social phobia, panic/agoraphobia, physical injury fears, and obsessive–compulsive subscales (b) participants with CdLS on separation anxiety, generalized anxiety, panic/agoraphobia, physical injury fears and obsessive–compulsive subscales, and (c) participants with RTS on panic/agoraphobia and obsessive–compulsive subscales. The results highlight divergent profiles of anxiety symptomatology between these groups.

KW - Anxiety

KW - Cornelia de Lange syndrome

KW - Fragile X syndrome

KW - Genetic syndromes

KW - Intellectual disability

KW - Rubinstein–Taybi syndrome

UR - http://www.scopus.com/inward/record.url?scp=85011258315&partnerID=8YFLogxK

U2 - 10.1007/s10803-016-3015-y

DO - 10.1007/s10803-016-3015-y

M3 - Article

AN - SCOPUS:85011258315

VL - 47

SP - 3728

EP - 3740

JO - Journal of Autism and Developmental Disorders

JF - Journal of Autism and Developmental Disorders

SN - 0162-3257

IS - 12

ER -