Abstract
Using targeted single-cell DNA sequencing approaches, two articles in Nature and Nature Communications have now firmly established that acute myeloid leukemia is a highly dynamic oligoclonal disease. Clonal evolution during disease progression and therapy occurs in both linear and branched trajectories, with a clear order of mutational events.
Original language | English |
---|---|
Pages (from-to) | 782-784 |
Number of pages | 3 |
Journal | Cancer Cell |
Volume | 38 |
Issue number | 6 |
DOIs | |
Publication status | Published - 14 Dec 2020 |
ASJC Scopus subject areas
- Oncology
- Cell Biology
- Cancer Research