Discrete multi-physics: A mesh-free model of blood flow in flexible biological valve including solid aggregate formation

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Discrete multi-physics : A mesh-free model of blood flow in flexible biological valve including solid aggregate formation. / Ariane, Mostapha; Allouche, Mohamed Hatem; Bussone, Marco; Giacosa, Fausto; Bernard, Frédéric; Barigou, Mostafa; Alexiadis, Alessio.

In: PLoS ONE, Vol. 12, No. 4, e0174795, 06.04.2017.

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Ariane, Mostapha ; Allouche, Mohamed Hatem ; Bussone, Marco ; Giacosa, Fausto ; Bernard, Frédéric ; Barigou, Mostafa ; Alexiadis, Alessio. / Discrete multi-physics : A mesh-free model of blood flow in flexible biological valve including solid aggregate formation. In: PLoS ONE. 2017 ; Vol. 12, No. 4.

Bibtex

@article{5d32b071796f4705aa9caebfcc62127d,
title = "Discrete multi-physics: A mesh-free model of blood flow in flexible biological valve including solid aggregate formation",
abstract = "We propose a mesh-free and discrete (particle-based) multi-physics approach for modelling the hydrodynamics in flexible biological valves. In the first part of this study, the method is successfully validated against both traditional modelling techniques and experimental data. In the second part, it is further developed to account for the formation of solid aggregates in the flow and at the membrane surface. Simulations of various types of aggregates highlight the main benefits of discrete multi-physics and indicate the potential of this approach for coupling the hydrodynamics with phenomena such as clotting and calcification in biological valves.",
author = "Mostapha Ariane and Allouche, {Mohamed Hatem} and Marco Bussone and Fausto Giacosa and Fr{\'e}d{\'e}ric Bernard and Mostafa Barigou and Alessio Alexiadis",
year = "2017",
month = apr,
day = "6",
doi = "10.1371/journal.pone.0174795",
language = "English",
volume = "12",
journal = "PLoSONE",
issn = "1932-6203",
publisher = "Public Library of Science (PLOS)",
number = "4",

}

RIS

TY - JOUR

T1 - Discrete multi-physics

T2 - A mesh-free model of blood flow in flexible biological valve including solid aggregate formation

AU - Ariane, Mostapha

AU - Allouche, Mohamed Hatem

AU - Bussone, Marco

AU - Giacosa, Fausto

AU - Bernard, Frédéric

AU - Barigou, Mostafa

AU - Alexiadis, Alessio

PY - 2017/4/6

Y1 - 2017/4/6

N2 - We propose a mesh-free and discrete (particle-based) multi-physics approach for modelling the hydrodynamics in flexible biological valves. In the first part of this study, the method is successfully validated against both traditional modelling techniques and experimental data. In the second part, it is further developed to account for the formation of solid aggregates in the flow and at the membrane surface. Simulations of various types of aggregates highlight the main benefits of discrete multi-physics and indicate the potential of this approach for coupling the hydrodynamics with phenomena such as clotting and calcification in biological valves.

AB - We propose a mesh-free and discrete (particle-based) multi-physics approach for modelling the hydrodynamics in flexible biological valves. In the first part of this study, the method is successfully validated against both traditional modelling techniques and experimental data. In the second part, it is further developed to account for the formation of solid aggregates in the flow and at the membrane surface. Simulations of various types of aggregates highlight the main benefits of discrete multi-physics and indicate the potential of this approach for coupling the hydrodynamics with phenomena such as clotting and calcification in biological valves.

UR - http://www.scopus.com/inward/record.url?scp=85017098713&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0174795

DO - 10.1371/journal.pone.0174795

M3 - Article

AN - SCOPUS:85017098713

VL - 12

JO - PLoSONE

JF - PLoSONE

SN - 1932-6203

IS - 4

M1 - e0174795

ER -