Dilemmas in undertaking research in paediatric intensive care

Research output: Contribution to journalReview articlepeer-review

Authors

Colleges, School and Institutes

External organisations

  • Guy's and St Thomas' NHS Foundation Trust
  • Birmingham Children’s Hospital NHS Foundation Trust,

Abstract

Providing evidence-based interventions for infants and children is important in paediatric intensive care, where decision making impacts most acutely on morbidity and mortality. However, despite the major progress of medicine in the 21st century, we still lack this evidence for majority of the decisions we make. In this article, we explore and suggest possible solutions for several dilemmas faced by paediatric intensive care researchers. These include ethical dilemmas such as validity of informed consent, use of deferred consent, balancing risk versus benefit and methodological dilemmas such as how to generate high-quality evidence with low-patient volume, choice of valid outcome measures and how best to use research and researchers' networks.

Details

Original languageEnglish
Pages (from-to)1043-1049
Number of pages7
JournalArchives of Disease in Childhood
Volume99
Issue number11
Early online date11 Jun 2014
Publication statusPublished - Nov 2014