Development of patch clamping

Research output: Chapter in Book/Report/Conference proceedingChapter


Colleges, School and Institutes

External organisations

  • London Centre for Nanotechnology


Patch clamping was first introduced into biophysical studies by Neher and Sakmann [1] in 1976 and was soon expanded to many other fields such as biology and medicine. The technique not only allowed the detection of single-channel currents in biological membranes for the first time but also enabled higher current resolution, direct membrane patch potential control, and physical isolation of membrane patches [2]. The development of the patch clamp method was honoured with a Nobel Prize in 1991.


Original languageEnglish
Title of host publicationSpringerBriefs in Applied Sciences and Technology
Publication statusPublished - 1 Jan 2014

Publication series

NameSpringerBriefs in Applied Sciences and Technology
ISSN (Print)2191-530X
ISSN (Electronic)2191-5318