Detection of DNA base variation and cytosine methylation at a single nucleotide site using a highly sensitive fluorescent probe.

Research output: Contribution to journalArticle

Authors

  • JL Duprey
  • ZY Zhao
  • DM Bassani
  • Jack Manchester
  • JS Vyle

Colleges, School and Institutes

Abstract

A fluorescent DNA probe containing an anthracene group attached via an anucleosidic linker can identify all four DNA bases at a single site as well as the epigenetic modification C/5-MeC via a hybridisation sensing assay.

Details

Original languageEnglish
JournalChemical Communications
Publication statusPublished - 12 May 2011