Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe

Research output: Contribution to journalArticle

Authors

  • DM Bassani
  • J-P Desvergne
  • S Keiper
  • PAS Lowden
  • JS Vyle

Colleges, School and Institutes

Abstract

A novel anthracene-tagged oligonucleotide can discriminate between a fully-matched DNA target sequence and one with a single mismatching base-pair through a remarkable difference in fluorescence emission intensity upon duplex formation.

Details

Original languageEnglish
Pages (from-to)5003-5005
Number of pages3
JournalChemical Communications
Volume2006
Publication statusPublished - 1 Jan 2006