Designing antigens for the prevention and treatment of autoimmune diseases

Research output: Contribution to journalArticlepeer-review


Colleges, School and Institutes


Antigen-specific immunotherapy is considered the holy-grail for treatment of autoimmune diseases. However, unlike the unattainable myth of Arthurian legend, effective antigen-specific immunotherapy is now being realised through clinical trials in patients. This review describes the various approaches being taken, how antigens are being designed for therapy and carriers created for their delivery. A critical assessment is made concerning the need for such carrier systems.


Original languageEnglish
Pages (from-to)35-42
Number of pages8
JournalCurrent Opinion in Chemical Engineering
Early online date28 Dec 2017
Publication statusPublished - Mar 2018

ASJC Scopus subject areas