Depression and schizophrenia: cause, consequence or trans-diagnostic issue?
Research output: Contribution to journal › Review article › peer-review
Colleges, School and Institutes
- e School of Clinical and Experimental Medicine , Institute of Clinical Sciences , University of Birmingham , Birmingham , UK.
- The Early Intervention in Psychosis Service, Birmingham and Solihull Mental Health Foundation Trust, Birmingham, UK.
- Mental Health and Wellbeing, Division of Health Sciences,Warwick Medical School, University of Warwick,Coventry,UK.
The presence of depression in schizophrenia has been a challenge to the Kraepelinian dichotomy, with various attempts to save the fundamental distinction including evoking and refining diagnoses such as schizoaffective disorder. But the tectonic plates are shifting. Here we put forward a summary of recent evidence regarding the prevalence, importance, possible aetiological pathways and treatment challenges that recognising depression in schizophrenia bring. Taken together we propose that depression is more than co-morbidity and that increased effective therapeutic attention to mood symptoms will be needed to improve outcomes and to support prevention.
|Number of pages||5|
|Early online date||15 Jul 2016|
|Publication status||Published - 1 Mar 2017|
- Comorbidity, Depressive Disorder/epidemiology, Humans, Psychotic Disorders/complications, Schizophrenia/complications