Decreased breast cancer risk in systemic lupus erythematosus: the search for a genetic basis continues

Research output: Contribution to journalArticlepeer-review

Authors

  • S Bernatsky
  • D F Easton
  • A Dunning
  • K Michailidou
  • R Ramsey-Goldman
  • C Gordon
  • A E Clarke
  • W Foulkes

Colleges, School and Institutes

Abstract

Recent work has demonstrated an important decrease in breast cancers for women with systemic lupus erythematosus (SLE). The reason behind this phenomenon is unknown. Our purpose was to explore whether the single nucleotide polymorphisms (SNPs) predisposing to SLE might be protective against breast cancer (in women in the general population).

Details

Original languageEnglish
Pages (from-to)896-9
Number of pages4
JournalLupus
Volume21
Issue number8
Publication statusPublished - Jul 2012

Keywords

  • Alleles, Breast Neoplasms, European Continental Ancestry Group, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Lupus Erythematosus, Systemic, Odds Ratio, Polymorphism, Single Nucleotide, Risk Factors