Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells

Research output: Contribution to journalArticlepeer-review


  • Lou-Ella M. M. Alexander
  • January Watters
  • Jessica A. Reusch
  • Michelle Maurin
  • Brook S. Nepon-Sixt
  • Mark G. Alexandrow
  • Kenneth L. Wright

Colleges, School and Institutes

External organisations

  • Cancer Biology Ph.D. Program, University of South Florida
  • Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute
  • Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute


The data presented here are related to the research article entitled “Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival” (Alexander et al., 2017) [1]. The cited research article characterizes Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) expression in the B cell compartment and functional dependence in B lymphoma cell lines. This data report describes the mRNA expression pattern in a panel of cell lines representing the B cell compartment, supplementing the protein expression data presented in the associated research report. In addition, a reanalysis is presented of publicly available mRNA expression data from primary murine B cells to reveal dynamic regulation of the ELL family members post LPS stimulation (Barwick et al., 2016) [2]. The effect of ELL3 depletion on cell morphology, latent Epstein Barr Virus (EBV) lytic replication and differentiation markers in a Burkitt's lymphoma (BL) cell line cells are presented.


Original languageEnglish
Pages (from-to)222-227
JournalData in Brief
Early online date22 Sep 2017
Publication statusPublished - 1 Dec 2017


  • ELL3 , Transcription elongation , B-cell lymphoma , cell division , EBV