Damage to cerebellocortical pathways after closed head injury: A behavioural and magnetic resonance imaging study

Research output: Contribution to journalArticle

Authors

  • Patrick Haggard
  • Derick Wade
  • Sue Fowler
  • Alex Richardson
  • Philip Anslow
  • John Stein

Colleges, School and Institutes

External organisations

  • University of Oxford
  • Rivermead Rehabiitation Centre
  • Radcliffe Infirmary

Abstract

anatomical substrate of ataxia seen after severe head injury. Five patients were recruited from present and former inpatients at Rivermead Rehabilitation Centre. All patients had had a closed head injury and all had cerebeilar type ataxia. Four normal controls were also studied. Brain MRI, clinical examination, computer based recording, and analysis of visuomotor tracking were carried out. Focal damage was found in the superior cerebellar peduncle in all five ataxic patients. The patients' tracking movements showed profound tremor, and unusual reliance on visual feedback. Ataxia seen after severe head injury can arise from damage to the superior cerebellar peduncle, which may interfere with the cerebelilocortical circuits involved in coordinated movement.

Details

Original languageEnglish
Pages (from-to)433-438
Number of pages6
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume58
Issue number4
Publication statusPublished - 1 Jan 1995

Keywords

  • Cerebellar ataxia, Cerebellar peduncles, Magnetic resonance imaging, Visuomotor tracking