Cytomegalovirus seropositivity is associated with increased arterial stiffness in patients with chronic kidney disease

Nadezhda A Wall, Colin D Chue, Nicola C Edwards, Tanya Pankhurst, Lorraine Harper, Richard P Steeds, Sarah Lauder, Jonathan N Townend, Paul Moss, Charles J Ferro

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

Patients with chronic kidney disease have an increased cardiovascular risk that is not fully explained by traditional risk factors but appears to be related to increased arterial stiffness. Cytomegalovirus (CMV) infection is associated with increased cardiovascular risk although the mechanisms for this are unknown. We examined whether CMV seropositivity was associated with increased arterial stiffness in patients with chronic kidney disease.
Original languageEnglish
Pages (from-to)e55686
JournalPLoS ONE
Volume8
Issue number2
DOIs
Publication statusPublished - 2013

Keywords

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antibodies, Viral
  • Blood Pressure
  • Cardiovascular Diseases
  • Cytomegalovirus
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Immunoglobulin G
  • Male
  • Middle Aged
  • Renal Insufficiency, Chronic
  • Risk Factors
  • Vascular Stiffness
  • Young Adult

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