Cu(OTf)2-catalysed Ritter reaction: Efficient synthesis of amides from nitriles and halohydrocarbons in water

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Authors

Colleges, School and Institutes

Abstract

An efficient and green protocol for the synthesis of amides through the Ritter reaction of nitriles and halohydrocarbons was developed. Cu(OTf) economically efficiently catalysed the Ritter reaction in water. A range of halohydrocarbons (benzyl, tert-butyl, sec-alkyl and primary alkyl halohydrocarbons) were coupled with nitriles, providing the corresponding amides. This journal is

Details

Original languageEnglish
Pages (from-to)6161-6163
Number of pages3
JournalRSC Advances
Volume2
Issue number15
Publication statusPublished - 7 Aug 2012