Abstract
An efficient and green protocol for the synthesis of amides through the Ritter reaction of nitriles and halohydrocarbons was developed. Cu(OTf) economically efficiently catalysed the Ritter reaction in water. A range of halohydrocarbons (benzyl, tert-butyl, sec-alkyl and primary alkyl halohydrocarbons) were coupled with nitriles, providing the corresponding amides. This journal is
Original language | English |
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Pages (from-to) | 6161-6163 |
Number of pages | 3 |
Journal | RSC Advances |
Volume | 2 |
Issue number | 15 |
DOIs | |
Publication status | Published - 7 Aug 2012 |