Controlled Assembly of Artificial Protein-Protein Complexes via DNA Duplex Formation
Research output: Contribution to journal › Article › peer-review
Colleges, School and Institutes
DNA–protein conjugates have found a wide range of applications. This study demonstrates the formation of defined, non-native protein–protein complexes via the site specific labeling of two proteins of interest with complementary strands of single-stranded DNA in vitro. This study demonstrates that the affinity of two DNA–protein conjugates for one another may be tuned by the use of variable lengths of DNA allowing reversible control of complex formation.
|Number of pages||8|
|Publication status||Published - 20 Jan 2015|