Controllable generation and encapsulation of alginate fibers using droplet-based microfluidics

Chiara Martino; Cyril Statzer; Daniele Vigolo; Andrew J. DeMello

doi:10.1039/c5lc01150g

Controllable generation and encapsulation of alginate fibers using droplet-based microfluidics

Chiara Martino^*, Cyril Statzer, Daniele Vigolo, Andrew J. DeMello

^*Corresponding author for this work

The University of Birmingham

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

Herein we demonstrate the segmentation of alginate solution streams to generate alginate fibers of precisely controllable lengths between 200 and 1000 μm. Moreover, we demonstrate the subsequent encapsulation of the formed fibers within pL-volume microdroplets, produced within the same microfluidic device, in a direct manner. Finally, we show immediate and complete on-chip gelation of alginate fibers in a rapid and reproducible fashion.

Original language	English
Pages (from-to)	59-64
Number of pages	6
Journal	Lab on a Chip
Volume	16
Issue number	1
Early online date	6 Nov 2015
DOIs	https://doi.org/10.1039/c5lc01150g
Publication status	Published - 7 Jan 2016

ASJC Scopus subject areas

Biochemistry
General Chemistry
Bioengineering
Biomedical Engineering

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Controllable generation and encapsulation of alginate fibers using droplet-based microfluidics

Abstract

ASJC Scopus subject areas

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