Consumer safety considerations of skin and oral microbiome perturbation
Research output: Contribution to journal › Review article › peer-review
Colleges, School and Institutes
- University of Manchester
Microbiomes associated with human skin and the oral cavity are uniquely exposed to personal care regimes. Changes in the composition and activities of the microbial communities in these environments can be utilized to promote consumer health benefits, for example, by reducing the numbers, composition, or activities of microbes implicated in conditions such as acne, axillary odor, dandruff, and oral diseases. It is, however, important to ensure that innovative approaches for microbiome manipulation do not unsafely disrupt the microbiome or compromise health, and where major changes in the composition or activities of the microbiome may occur, these require evaluation to ensure that critical biological functions are unaffected. This article is based on a 2-day workshop held at SEAC Unilever, Sharnbrook, United Kingdom, involving 31 specialists in microbial risk assessment, skin and oral microbiome research, microbial ecology, bioinformatics, mathematical modeling, and immunology. The first day focused on understanding the potential implications of skin and oral microbiome perturbation, while approaches to characterize those perturbations were discussed during the second day. This article discusses the factors that the panel recommends be considered for personal care products that target the microbiomes of the skin and the oral cavity.
Copyright © 2019 American Society for Microbiology.
|Journal||Clinical Microbiology Reviews|
|Early online date||31 Jul 2019|
|Publication status||Published - Oct 2019|
- Consumer safety, Hygiene, Oral microbiome, Personal care, Risk assessment, Skin microbiome