Construction of DNA-polymer hybrids using intercalation interactions
Research output: Contribution to journal › Article › peer-review
Colleges, School and Institutes
Reversible addition–fragmentation chain transfer (RAFT) polymerisation was used to produce a range of polymers terminated with an acridine group, which intercalates efficiently into dsDNA; the structure of the polymer determines the nature and strength of the interaction. Using a short 63 base pair dsDNA, discrete and well-defined DNA–polymer hybrid nanoparticles were formed, which were characterised by dynamic light scattering, small-angle X-ray scattering and atomic force microscopy.
|Number of pages||3|
|Early online date||17 Dec 2013|
|Publication status||Published - 2014|