Conduct disorder

Research output: Contribution to journalReview article

Standard

Conduct disorder. / Fairchild, Graeme; Hawes, David; Frick, Paul; Copeland, William; Odgers, Candice; Franke, Barbara; Freitag, Christine; De Brito, Stephane.

In: Nature Reviews Disease Primers, Vol. 5, No. 1, 43 , 01.12.2019.

Research output: Contribution to journalReview article

Harvard

Fairchild, G, Hawes, D, Frick, P, Copeland, W, Odgers, C, Franke, B, Freitag, C & De Brito, S 2019, 'Conduct disorder', Nature Reviews Disease Primers, vol. 5, no. 1, 43 . https://doi.org/10.1038/s41572-019-0095-y

APA

Fairchild, G., Hawes, D., Frick, P., Copeland, W., Odgers, C., Franke, B., Freitag, C., & De Brito, S. (2019). Conduct disorder. Nature Reviews Disease Primers, 5(1), [43 ]. https://doi.org/10.1038/s41572-019-0095-y

Vancouver

Fairchild G, Hawes D, Frick P, Copeland W, Odgers C, Franke B et al. Conduct disorder. Nature Reviews Disease Primers. 2019 Dec 1;5(1). 43 . https://doi.org/10.1038/s41572-019-0095-y

Author

Fairchild, Graeme ; Hawes, David ; Frick, Paul ; Copeland, William ; Odgers, Candice ; Franke, Barbara ; Freitag, Christine ; De Brito, Stephane. / Conduct disorder. In: Nature Reviews Disease Primers. 2019 ; Vol. 5, No. 1.

Bibtex

@article{844f8215f7fa4f4cbbc180007235ff07,
title = "Conduct disorder",
abstract = "Conduct disorder (CD) is a common and highly impairing psychiatric disorder that usually emerges in childhood or adolescence and is characterized by severe antisocial and aggressive behaviour. It frequently co-occurs with attention-deficit/hyperactivity disorder (ADHD) and often leads to antisocial personality disorder in adulthood. CD affects ~3% of school-aged children and is twice as prevalent in males than in females. This disorder can be subtyped according to age at onset (childhood-onset versus adolescent-onset) and the presence or absence of callous-unemotional traits (deficits in empathy and guilt). The aetiology of CD is complex, with contributions of both genetic and environmental risk factors and different forms of interplay among the two (gene–environment interaction and correlation). In addition, CD is associated with neurocognitive impairments; smaller grey matter volume in limbic regions such as the amygdala, insula and orbitofrontal cortex, and functional abnormalities in overlapping brain circuits responsible for emotion processing, emotion regulation and reinforcement-based decision-making have been reported. Lower hypothalamic–pituitary–adrenal axis and autonomic reactivity to stress has also been reported. Management of CD primarily involves parent-based or family-based psychosocial interventions, although stimulants and atypical antipsychotics are sometimes used, especially in individuals with comorbid ADHD.",
author = "Graeme Fairchild and David Hawes and Paul Frick and William Copeland and Candice Odgers and Barbara Franke and Christine Freitag and {De Brito}, Stephane",
year = "2019",
month = dec
day = "1",
doi = "10.1038/s41572-019-0095-y",
language = "English",
volume = "5",
journal = "Nature Reviews Disease Primers",
issn = "2056-676X",
publisher = "Nature Publishing Group",
number = "1",

}

RIS

TY - JOUR

T1 - Conduct disorder

AU - Fairchild, Graeme

AU - Hawes, David

AU - Frick, Paul

AU - Copeland, William

AU - Odgers, Candice

AU - Franke, Barbara

AU - Freitag, Christine

AU - De Brito, Stephane

PY - 2019/12/1

Y1 - 2019/12/1

N2 - Conduct disorder (CD) is a common and highly impairing psychiatric disorder that usually emerges in childhood or adolescence and is characterized by severe antisocial and aggressive behaviour. It frequently co-occurs with attention-deficit/hyperactivity disorder (ADHD) and often leads to antisocial personality disorder in adulthood. CD affects ~3% of school-aged children and is twice as prevalent in males than in females. This disorder can be subtyped according to age at onset (childhood-onset versus adolescent-onset) and the presence or absence of callous-unemotional traits (deficits in empathy and guilt). The aetiology of CD is complex, with contributions of both genetic and environmental risk factors and different forms of interplay among the two (gene–environment interaction and correlation). In addition, CD is associated with neurocognitive impairments; smaller grey matter volume in limbic regions such as the amygdala, insula and orbitofrontal cortex, and functional abnormalities in overlapping brain circuits responsible for emotion processing, emotion regulation and reinforcement-based decision-making have been reported. Lower hypothalamic–pituitary–adrenal axis and autonomic reactivity to stress has also been reported. Management of CD primarily involves parent-based or family-based psychosocial interventions, although stimulants and atypical antipsychotics are sometimes used, especially in individuals with comorbid ADHD.

AB - Conduct disorder (CD) is a common and highly impairing psychiatric disorder that usually emerges in childhood or adolescence and is characterized by severe antisocial and aggressive behaviour. It frequently co-occurs with attention-deficit/hyperactivity disorder (ADHD) and often leads to antisocial personality disorder in adulthood. CD affects ~3% of school-aged children and is twice as prevalent in males than in females. This disorder can be subtyped according to age at onset (childhood-onset versus adolescent-onset) and the presence or absence of callous-unemotional traits (deficits in empathy and guilt). The aetiology of CD is complex, with contributions of both genetic and environmental risk factors and different forms of interplay among the two (gene–environment interaction and correlation). In addition, CD is associated with neurocognitive impairments; smaller grey matter volume in limbic regions such as the amygdala, insula and orbitofrontal cortex, and functional abnormalities in overlapping brain circuits responsible for emotion processing, emotion regulation and reinforcement-based decision-making have been reported. Lower hypothalamic–pituitary–adrenal axis and autonomic reactivity to stress has also been reported. Management of CD primarily involves parent-based or family-based psychosocial interventions, although stimulants and atypical antipsychotics are sometimes used, especially in individuals with comorbid ADHD.

UR - http://www.scopus.com/inward/record.url?scp=85068092827&partnerID=8YFLogxK

U2 - 10.1038/s41572-019-0095-y

DO - 10.1038/s41572-019-0095-y

M3 - Review article

VL - 5

JO - Nature Reviews Disease Primers

JF - Nature Reviews Disease Primers

SN - 2056-676X

IS - 1

M1 - 43

ER -