Colorectal cancer, screening and survival: the influence of socio-economic deprivation

Research output: Contribution to journalArticle


  • Emma Frew
  • DK Whynes
  • CM Manghan
  • JH Scholefield
  • JD Hardcastle


OBJECTIVES: To determine the extent to which socio-economic deprivation explains colorectal cancer prevalence, subject participation in screening, and postoperative survival and life expectancy. METHODS: Regression analyses of clinical data from a large randomized controlled trial, augmented by geographical-based indices of deprivation. RESULTS: Deprivation appears to exert no significant impact on colorectal cancer prevalence but is a major factor explaining subject participation in screening. Cancer detection at later stages reduces life expectancy at time of treatment. Females from more-deprived areas have poorer post-treatment life expectancies and survival prospects, independently of their screening behaviour. CONCLUSIONS: Screening increases the chances of having a cancer treated at an earlier stage, and treatment at an earlier stage is associated with longer subsequent life expectancy. However, those from more-deprived areas are less likely to accept an invitation to be screened.


Original languageEnglish
Pages (from-to)389-95
Number of pages7
JournalPublic Health
Issue number6
Publication statusPublished - 1 Nov 2003

Sustainable Development Goals