Cold acclimation induces physiological cardiac hypertrophy and increases assimilation of triacylglycerol metabolism through lipoprotein lipase.

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Colleges, School and Institutes

Abstract

The contribution of triacylglycerol to energy provision in the hypertrophied heart, mediated through lipoprotein lipase (LPL) is largely unknown and the contribution of very-low-density lipoprotein (VLDL) receptor to control of LPL presentation at the endothelium is unclear. For isolated perfused rat hearts, cold acclimation (CA) induced volume-overload hypertrophy, with decreased developed pressure (P

Details

Original languageEnglish
Pages (from-to)618-26
Number of pages9
JournalBiochimica et Biophysica Acta
Volume1781
Issue number10
Publication statusPublished - 1 Oct 2008

Keywords

  • Cardiac hypertrophy, AMPK, Very-low-density lipoprotein receptor, Triacylglycerol