Cognitive deterioration in adults with down syndrome: Effects on the individual, caregivers, and service use

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Colleges, School and Institutes


Individuals with Down syndrome (N = 49) who had participated in serial neuropsychological assessments were assigned to one of three groups comparable in level of premorbid mental retardation: those showing cognitive deterioration, those comparable in age but not showing cognitive deterioration, and those not showing cognitive deterioration but younger. Those experiencing cognitive deterioration were less likely to receive day services, had more impoverished life experiences, and required more support compared to groups without cognitive deterioration. When age was controlled for, cognitive deterioration was significantly positively associated with caregiver difficulties and service use and negatively associated with life experiences for the individual. Results suggest a potential role for caregiver difficulties in influencing life experiences of adults with Down syndrome showing cognitive decline.


Original languageEnglish
Pages (from-to)455-465
Number of pages11
JournalAmerican Journal on Mental Retardation
Issue number6
Publication statusPublished - 1 Jan 2000