Clinical risk factors of oral leukoplakia in a representative sample of the US population

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Clinical risk factors of oral leukoplakia in a representative sample of the US population. / Dietrich, Thomas; Reichart, PA; Scheifele, C.

In: Oral Oncology, Vol. 40, No. 2, 01.02.2004, p. 158-163.

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@article{4a571dee6e8f4a5ead45a3dfe988e143,
title = "Clinical risk factors of oral leukoplakia in a representative sample of the US population",
abstract = "Studies on the risk factors of oral leukoplakia (OL) are relatively scarce. The objectives of this paper are to assess the clinical risk factors of OL in a representative sample of the US population. Data from the oral mucosal tissue assessment and some other covariates of 15,811 participants in the US National Health and Nutrition Examination Survey (NHANES III) were included. The clinical definition of OL was applied according to the WHO criteria. Tobacco smoking was found as the strongest independent risk factor. The OR were 3.00 (0.77-11.8) for 20 cigarettes/day. Diabetes, age and socio-economic status were found as independent predictors of OL. Alcohol consumption, race/ethnicity, years of education and BMI showed no independent association with OL. Females with a history of estrogen use were less likely to have OL with an OR of 0.34 (0.11-1.07). In conclusion, the role of diabetes and estrogen in the pathogenesis of OL should be further investigated.",
author = "Thomas Dietrich and PA Reichart and C Scheifele",
year = "2004",
month = feb,
day = "1",
doi = "10.1016/S1368-8375(03)00145-3",
language = "English",
volume = "40",
pages = "158--163",
journal = "Oral Oncology",
issn = "1368-8375",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - Clinical risk factors of oral leukoplakia in a representative sample of the US population

AU - Dietrich, Thomas

AU - Reichart, PA

AU - Scheifele, C

PY - 2004/2/1

Y1 - 2004/2/1

N2 - Studies on the risk factors of oral leukoplakia (OL) are relatively scarce. The objectives of this paper are to assess the clinical risk factors of OL in a representative sample of the US population. Data from the oral mucosal tissue assessment and some other covariates of 15,811 participants in the US National Health and Nutrition Examination Survey (NHANES III) were included. The clinical definition of OL was applied according to the WHO criteria. Tobacco smoking was found as the strongest independent risk factor. The OR were 3.00 (0.77-11.8) for 20 cigarettes/day. Diabetes, age and socio-economic status were found as independent predictors of OL. Alcohol consumption, race/ethnicity, years of education and BMI showed no independent association with OL. Females with a history of estrogen use were less likely to have OL with an OR of 0.34 (0.11-1.07). In conclusion, the role of diabetes and estrogen in the pathogenesis of OL should be further investigated.

AB - Studies on the risk factors of oral leukoplakia (OL) are relatively scarce. The objectives of this paper are to assess the clinical risk factors of OL in a representative sample of the US population. Data from the oral mucosal tissue assessment and some other covariates of 15,811 participants in the US National Health and Nutrition Examination Survey (NHANES III) were included. The clinical definition of OL was applied according to the WHO criteria. Tobacco smoking was found as the strongest independent risk factor. The OR were 3.00 (0.77-11.8) for 20 cigarettes/day. Diabetes, age and socio-economic status were found as independent predictors of OL. Alcohol consumption, race/ethnicity, years of education and BMI showed no independent association with OL. Females with a history of estrogen use were less likely to have OL with an OR of 0.34 (0.11-1.07). In conclusion, the role of diabetes and estrogen in the pathogenesis of OL should be further investigated.

U2 - 10.1016/S1368-8375(03)00145-3

DO - 10.1016/S1368-8375(03)00145-3

M3 - Article

C2 - 14693239

VL - 40

SP - 158

EP - 163

JO - Oral Oncology

JF - Oral Oncology

SN - 1368-8375

IS - 2

ER -