Clinical review: clinical management of atrial fibrillation - rate control versus rhythm control

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Colleges, School and Institutes


Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in the critically ill and is associated with adverse outcomes. Although there are plausible benefits from conversion and maintenance of sinus rhythm (the so-called 'rhythm-control' strategy), recent randomized trials have failed to demonstrate the superiority of this approach over the rate-control strategy. Regardless of approach, continuous therapeutic anticoagulation is crucial for stroke prevention. This review addresses the findings of these studies and their implications for clinical management of patients with atrial fibrillation.


Original languageEnglish
Pages (from-to)271-9
Number of pages9
JournalJournal of Human Hypertension
Issue number4
Publication statusPublished - 1 Aug 2004