Clinical correlates of quality of life in Tourette syndrome

Research output: Contribution to journalArticle


  • Clare Eddy
  • M Gulisano
  • A Agodi
  • M Barchitta
  • P Calì
  • MM Robertson
  • R Rizzo

Colleges, School and Institutes


Tourette syndrome (TS) is a neurodevelopmental disorder involving tics, which is frequently accompanied by comorbid obsessive compulsive (OCD) or attention deficit hyperactivity disorder (ADHD). Individuals with TS often report poor quality of life (QoL) in comparison with the general population. This study investigated the clinical correlates of QoL in young people with TS using a self-report multidimensional QoL measure, and a range of clinical scales used to assess tic severity and the symptoms of anxiety, depression, OCD, ADHD and other emotional and behavioral symptoms. Symptoms of depression, OCD, and ADHD appeared to have a widespread negative impact on QoL, but poorer QoL was not associated with increased tic severity. Greater emotional and behavioral difficulties, including symptoms of OCD, were among the best predictors of poor QoL in young people with TS. © 2010 Movement Disorder Society.


Original languageEnglish
Pages (from-to)735-738
Number of pages4
JournalMovement Disorders
Publication statusPublished - 10 Nov 2010