Clinical and biochemical manifestations of Cushing's

Research output: Contribution to journalArticlepeer-review

Authors

Colleges, School and Institutes

Abstract

INTRODUCTION: Cushing's syndrome is associated with a number of clinical manifestations and co-morbidities which may not resolve even after long-term remission leading to excessive mortality.

MATERIALS AND METHODS: This review summarizes the main manifestations of Cushing's syndrome (active or in remission) with particular focus on data from recently published literature.

CONCLUSION: Obesity and metabolic alterations, hypertension and cardio/cerebrovascular complications, hypercoagulability/thromboembolism, neuropsychiatric, muscle/skeletal and immune consequences remain the most challenging. Cardiovascular consequences and immunosuppression determine the main causes of death in Cushing's syndrome necessitating early intervention when possible.

Details

Original languageEnglish
Pages (from-to)181-187
Number of pages7
JournalPituitary
Volume18
Issue number2
Early online date10 Jan 2015
Publication statusPublished - Apr 2015