Clarithromycin alone and in combination with ceftriaxone inhibits the production of pneumolysin by both macrolide-susceptible and macrolide-resistant strains of Streptococcus pneumoniae
Research output: Contribution to journal › Article
Authors
Colleges, School and Institutes
Abstract
To investigate the effects of clarithromycin (0.01-0.5 mg/L) alone or in combination with ceftriaxone (0.1 and 0.25 mg/L) on pneumolysin production by both macrolide-susceptible and -resistant [2 erm(B) positive and 2 mef(A) positive] strains of Streptococcus pneumoniae.
Details
| Original language | English |
|---|---|
| Pages (from-to) | 224-9 |
| Number of pages | 6 |
| Journal | Journal of Antimicrobial Chemotherapy |
| Volume | 59 |
| Issue number | 2 |
| Publication status | Published - Feb 2007 |
Keywords
- Anti-Bacterial Agents, Bacterial Proteins, Ceftriaxone, Clarithromycin, Dose-Response Relationship, Drug, Drug Resistance, Bacterial, Drug Synergism, Microbial Sensitivity Tests, Polymerase Chain Reaction, Streptococcus pneumoniae, Streptolysins