Chronic suppurative otitis media in Nepal: ethnicity does not determine whether disease is associated with cholesteatoma or not

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Chronic suppurative otitis media in Nepal: ethnicity does not determine whether disease is associated with cholesteatoma or not. / Thornton, D; Martin, Thomas; Amin, P; Haque, Mohammad; Wilson, Sue; Smith, M C F.

In: The Journal of laryngology and otology, Vol. 125, No. 01, 01.01.2011, p. 22-26.

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@article{434eee85e63a47a7a4a053c847b1db99,
title = "Chronic suppurative otitis media in Nepal:: ethnicity does not determine whether disease is associated with cholesteatoma or not",
abstract = "Objectives:To determine the frequency of cholesteatoma in a population of patients with chronic suppurative otitis media, and to determine whether this frequency is affected by ethnicity.Patients:The study included 6005 patients with chronic suppurative otitis media seen during the course of 30 charitable surgical 'ear camps' in Nepal.Main outcome measures:Proportion of patients with each subtype of disease, and their ethnicity. A secondary outcome measure was concordance of surname with Nepalese ethnic affiliation.Results:A total of 762 patients were grouped as being of Tibeto-Mongolian origin, and 4875 as Indo-Caucasian. The rate of chronic suppurative otitis media with cholesteatoma, expressed as a proportion of the rate of all chronic suppurative otitis media subtypes, was 17.8 per cent in Tibeto-Mongolian patients and 18.6 per cent in Indo-Caucasian patients (p > 0.05). The effect of other risk factors (i.e. age, gender and geographical district) on disease distribution was also non-significant. Analysis of secondary outcome measures indicated that patients' surnames were a reliable predictor of ethnicity in this Nepalese population.Conclusion:There is almost complete concordance in proportions of patients with significant genetic, cultural, and even geographical heterogeneity, suggesting that, in Nepal, the aetiology of cholesteatoma owes little to these factors.",
keywords = "Ethnicity , Nepal , Otitis media , Suppurative",
author = "D Thornton and Thomas Martin and P Amin and Mohammad Haque and Sue Wilson and Smith, {M C F}",
year = "2011",
month = jan,
day = "1",
doi = "10.1017/S0022215110001878",
language = "English",
volume = "125",
pages = "22--26",
journal = "The Journal of laryngology and otology",
issn = "0022-2151",
publisher = "Cambridge University Press",
number = "01",

}

RIS

TY - JOUR

T1 - Chronic suppurative otitis media in Nepal:

T2 - ethnicity does not determine whether disease is associated with cholesteatoma or not

AU - Thornton, D

AU - Martin, Thomas

AU - Amin, P

AU - Haque, Mohammad

AU - Wilson, Sue

AU - Smith, M C F

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Objectives:To determine the frequency of cholesteatoma in a population of patients with chronic suppurative otitis media, and to determine whether this frequency is affected by ethnicity.Patients:The study included 6005 patients with chronic suppurative otitis media seen during the course of 30 charitable surgical 'ear camps' in Nepal.Main outcome measures:Proportion of patients with each subtype of disease, and their ethnicity. A secondary outcome measure was concordance of surname with Nepalese ethnic affiliation.Results:A total of 762 patients were grouped as being of Tibeto-Mongolian origin, and 4875 as Indo-Caucasian. The rate of chronic suppurative otitis media with cholesteatoma, expressed as a proportion of the rate of all chronic suppurative otitis media subtypes, was 17.8 per cent in Tibeto-Mongolian patients and 18.6 per cent in Indo-Caucasian patients (p > 0.05). The effect of other risk factors (i.e. age, gender and geographical district) on disease distribution was also non-significant. Analysis of secondary outcome measures indicated that patients' surnames were a reliable predictor of ethnicity in this Nepalese population.Conclusion:There is almost complete concordance in proportions of patients with significant genetic, cultural, and even geographical heterogeneity, suggesting that, in Nepal, the aetiology of cholesteatoma owes little to these factors.

AB - Objectives:To determine the frequency of cholesteatoma in a population of patients with chronic suppurative otitis media, and to determine whether this frequency is affected by ethnicity.Patients:The study included 6005 patients with chronic suppurative otitis media seen during the course of 30 charitable surgical 'ear camps' in Nepal.Main outcome measures:Proportion of patients with each subtype of disease, and their ethnicity. A secondary outcome measure was concordance of surname with Nepalese ethnic affiliation.Results:A total of 762 patients were grouped as being of Tibeto-Mongolian origin, and 4875 as Indo-Caucasian. The rate of chronic suppurative otitis media with cholesteatoma, expressed as a proportion of the rate of all chronic suppurative otitis media subtypes, was 17.8 per cent in Tibeto-Mongolian patients and 18.6 per cent in Indo-Caucasian patients (p > 0.05). The effect of other risk factors (i.e. age, gender and geographical district) on disease distribution was also non-significant. Analysis of secondary outcome measures indicated that patients' surnames were a reliable predictor of ethnicity in this Nepalese population.Conclusion:There is almost complete concordance in proportions of patients with significant genetic, cultural, and even geographical heterogeneity, suggesting that, in Nepal, the aetiology of cholesteatoma owes little to these factors.

KW - Ethnicity

KW - Nepal

KW - Otitis media

KW - Suppurative

U2 - 10.1017/S0022215110001878

DO - 10.1017/S0022215110001878

M3 - Article

C2 - 20875194

VL - 125

SP - 22

EP - 26

JO - The Journal of laryngology and otology

JF - The Journal of laryngology and otology

SN - 0022-2151

IS - 01

ER -