Chronic stimulation of the peroneal nerve in rats upregulates the pro-opiomelanocortin gene in spinal motoneurones

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Chronic stimulation of the peroneal nerve in rats upregulates the pro-opiomelanocortin gene in spinal motoneurones. / Hughes, Sharon; Shiner, RA; Smith, Margaret.

In: Brain Research, Vol. 887, No. 1, 01.12.2000, p. 191-193.

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@article{57cfc9ef82cf4e08b324e5bc7f89fb7d,
title = "Chronic stimulation of the peroneal nerve in rats upregulates the pro-opiomelanocortin gene in spinal motoneurones",
abstract = "Continuous unilateral stimulation of the peroneal nerve in rats for 8 h per day for 2 or 7 days caused significant increases in POMC mRNA and beta -endorphin immunoreactivity in bath ipsilateral and contralateral motoneurones. Intermittent stimulation, for 10-min periods with 90-min rest periods, for 8 h per day for 2 days also caused upregulation of POMC mRNA. It is suggested that expression of POMC-derived peptides in motoneurones may be important for maintaining muscle contractile function. (C) 2000 Elsevier Science BN. All rights reserved.",
keywords = "motoneuron, exercise, pro-opiomelanocortin, beta-endorphin, nerve stimulation",
author = "Sharon Hughes and RA Shiner and Margaret Smith",
year = "2000",
month = dec,
day = "1",
doi = "10.1016/S0006-8993(00)03055-9",
language = "English",
volume = "887",
pages = "191--193",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Chronic stimulation of the peroneal nerve in rats upregulates the pro-opiomelanocortin gene in spinal motoneurones

AU - Hughes, Sharon

AU - Shiner, RA

AU - Smith, Margaret

PY - 2000/12/1

Y1 - 2000/12/1

N2 - Continuous unilateral stimulation of the peroneal nerve in rats for 8 h per day for 2 or 7 days caused significant increases in POMC mRNA and beta -endorphin immunoreactivity in bath ipsilateral and contralateral motoneurones. Intermittent stimulation, for 10-min periods with 90-min rest periods, for 8 h per day for 2 days also caused upregulation of POMC mRNA. It is suggested that expression of POMC-derived peptides in motoneurones may be important for maintaining muscle contractile function. (C) 2000 Elsevier Science BN. All rights reserved.

AB - Continuous unilateral stimulation of the peroneal nerve in rats for 8 h per day for 2 or 7 days caused significant increases in POMC mRNA and beta -endorphin immunoreactivity in bath ipsilateral and contralateral motoneurones. Intermittent stimulation, for 10-min periods with 90-min rest periods, for 8 h per day for 2 days also caused upregulation of POMC mRNA. It is suggested that expression of POMC-derived peptides in motoneurones may be important for maintaining muscle contractile function. (C) 2000 Elsevier Science BN. All rights reserved.

KW - motoneuron

KW - exercise

KW - pro-opiomelanocortin

KW - beta-endorphin

KW - nerve stimulation

U2 - 10.1016/S0006-8993(00)03055-9

DO - 10.1016/S0006-8993(00)03055-9

M3 - Article

C2 - 11134605

VL - 887

SP - 191

EP - 193

JO - Brain Research

JF - Brain Research

SN - 0006-8993

IS - 1

ER -