Abstract
Continuous unilateral stimulation of the peroneal nerve in rats for 8 h per day for 2 or 7 days caused significant increases in POMC mRNA and beta -endorphin immunoreactivity in bath ipsilateral and contralateral motoneurones. Intermittent stimulation, for 10-min periods with 90-min rest periods, for 8 h per day for 2 days also caused upregulation of POMC mRNA. It is suggested that expression of POMC-derived peptides in motoneurones may be important for maintaining muscle contractile function. (C) 2000 Elsevier Science BN. All rights reserved.
Original language | English |
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Pages (from-to) | 191-193 |
Number of pages | 3 |
Journal | Brain Research |
Volume | 887 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 Dec 2000 |
Keywords
- motoneuron
- exercise
- pro-opiomelanocortin
- beta-endorphin
- nerve stimulation