Chemokines: leucocyte recruitment and activation cytokines
Research output: Contribution to journal › Article › peer-review
Chemokines are a family of structurally related proteins that share the ability to induce migration of specific subsets of leucocytes. These specialised cytokines play a critical part in the generation of cellular inflammation, both in the protective responses to invading pathogens and in the pathological processes associated with infection and immune-mediated diseases. Chemokines are more than simple chemotactic factors, since they are also implicated in leucocyte activation, angiogenesis, and antimicrobial functions, including a protective role in HIV infection. These molecules provide potentially valuable targets for therapeutic intervention in a wide range of diseases.
|Number of pages||6|
|Publication status||Published - 15 Feb 1997|
- Chemokines, Chemotactic Factors, Chemotaxis, Leukocyte, Cytokines, HIV Infections, Humans, Inflammation Mediators, Leukocytes