Challenges of biomolecular detection at the nanoscale: nanopores and microelectrodes

K. Mathwig; T. Albrecht; E.D. Goluch; L. Rassaei

doi:10.1021/acs.analchem.5b01167

Challenges of biomolecular detection at the nanoscale: nanopores and microelectrodes

K. Mathwig, T. Albrecht, E.D. Goluch, L. Rassaei

Chemistry

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

The interest in analytical devices, which typically rely on the reactivity of a biological component for specificity, is growing rapidly. In this Perspective, we highlight current challenges in all-electrical biosensing as these systems shrink toward the nanoscale and enable the detection of analytes at the single-molecule level. We focus on two sensing principles: nanopores and amperometric microelectrode devices.

Original language	English
Pages (from-to)	5470-5475
Number of pages	6
Journal	Analytical Chemistry
Volume	87
Issue number	11
Early online date	13 May 2015
DOIs	https://doi.org/10.1021/acs.analchem.5b01167
Publication status	Published - 2 Jun 2015

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https://doi.org/10.1021/acs.analchem.5b01167Licence: None: All rights reserved

Cite this

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abstract = "The interest in analytical devices, which typically rely on the reactivity of a biological component for specificity, is growing rapidly. In this Perspective, we highlight current challenges in all-electrical biosensing as these systems shrink toward the nanoscale and enable the detection of analytes at the single-molecule level. We focus on two sensing principles: nanopores and amperometric microelectrode devices.",

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