CASA: tracking the past and plotting the future

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CASA: tracking the past and plotting the future. / Gallagher, Meurig Thomas; Smith, David; Kirkman-Brown, Jackson.

In: Reproduction Fertility and Development, Vol. 30, No. 6, 29.05.2018, p. 867-874.

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@article{b158482a5d294cb89457e77452053e40,
title = "CASA:: tracking the past and plotting the future",
abstract = "The human semen sample carries a wealth of information of varying degrees of accessibility ranging from the traditional visual measures of count and motility to those that need a more computational approach, such as tracking the flagellar waveform. Although computer-aided sperm analysis (CASA) options are becoming more widespread, the gold standard for clinical semen analysis requires trained laboratory staff. In this review we characterise the key attitudes towards the use of CASA and set out areas in which CASA should, and should not, be used and improved. We provide an overview of the current CASA landscape, discussing clinical uses as well as potential areas for the clinical translation of existing research technologies. Finally, we discuss where we see potential for the future of CASA, and how the integration of mathematical modelling and new technologies, such as automated flagellar tracking, may open new doors in clinical semen analysis",
keywords = "clinical diagnostics, flagellar analysis, glyphs, image analysis, machine learning, mathematical modelling, sperm, viscosity",
author = "Gallagher, {Meurig Thomas} and David Smith and Jackson Kirkman-Brown",
year = "2018",
month = may,
day = "29",
doi = "10.1071/RD17420",
language = "English",
volume = "30",
pages = "867--874",
journal = "Reproduction Fertility and Development",
issn = "1031-3613",
publisher = "CSIRO Publishing",
number = "6",

}

RIS

TY - JOUR

T1 - CASA:

T2 - tracking the past and plotting the future

AU - Gallagher, Meurig Thomas

AU - Smith, David

AU - Kirkman-Brown, Jackson

PY - 2018/5/29

Y1 - 2018/5/29

N2 - The human semen sample carries a wealth of information of varying degrees of accessibility ranging from the traditional visual measures of count and motility to those that need a more computational approach, such as tracking the flagellar waveform. Although computer-aided sperm analysis (CASA) options are becoming more widespread, the gold standard for clinical semen analysis requires trained laboratory staff. In this review we characterise the key attitudes towards the use of CASA and set out areas in which CASA should, and should not, be used and improved. We provide an overview of the current CASA landscape, discussing clinical uses as well as potential areas for the clinical translation of existing research technologies. Finally, we discuss where we see potential for the future of CASA, and how the integration of mathematical modelling and new technologies, such as automated flagellar tracking, may open new doors in clinical semen analysis

AB - The human semen sample carries a wealth of information of varying degrees of accessibility ranging from the traditional visual measures of count and motility to those that need a more computational approach, such as tracking the flagellar waveform. Although computer-aided sperm analysis (CASA) options are becoming more widespread, the gold standard for clinical semen analysis requires trained laboratory staff. In this review we characterise the key attitudes towards the use of CASA and set out areas in which CASA should, and should not, be used and improved. We provide an overview of the current CASA landscape, discussing clinical uses as well as potential areas for the clinical translation of existing research technologies. Finally, we discuss where we see potential for the future of CASA, and how the integration of mathematical modelling and new technologies, such as automated flagellar tracking, may open new doors in clinical semen analysis

KW - clinical diagnostics

KW - flagellar analysis

KW - glyphs

KW - image analysis

KW - machine learning

KW - mathematical modelling

KW - sperm

KW - viscosity

U2 - 10.1071/RD17420

DO - 10.1071/RD17420

M3 - Review article

VL - 30

SP - 867

EP - 874

JO - Reproduction Fertility and Development

JF - Reproduction Fertility and Development

SN - 1031-3613

IS - 6

ER -