Cardiovascular and cortisol reactions to acute psychological stress and adiposity: Cross-sectional and prospective associations in the Dutch Famine Birth Cohort Study.

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@article{3e2646b9e2bf403ea594fd8570b6b4fb,
title = "Cardiovascular and cortisol reactions to acute psychological stress and adiposity: Cross-sectional and prospective associations in the Dutch Famine Birth Cohort Study.",
abstract = "Objective: In recent analyses of data from a large community sample, negative cross-sectional and prospective associations between cardiac stress reactivity and obesity were observed. The present study reexamined the association between cardiovascular reactivity and adiposity in the Dutch Famine Birth Cohort, with the additional aim of examining the association between cortisol reactivity and adiposity. Methods: Blood pressure, heart rate, and salivary cortisol were measured at rest and in response to standard laboratory stress tasks in 725 adults. Height, weight, waist-and-hip circumference, and skinfold thickness were measured. Between 4 to 7 years later, 460 participants reported current height and weight. Obesity was defined as a body mass index of 30 kg/m2 or higher. Results: Those with a greater body mass index (β = −0.39 beats per minute (bpm)), waist-to-hip ratio (β = −0.15 bpm), and triceps and subscapular skinfold thicknesses (β = −1.0 and −1.8 bpm) or who were categorized as obese (−3.9 bpm) displayed smaller cardiac reactions to acute stress (all p < .001). With the exception of waist-to-hip ratio, the same negative associations emerged for cortisol reactivity (all p ≤ .01). In prospective analyses, low cardiac reactivity was associated with an increased likelihood of becoming or remaining obese in the subsequent 4 to 7 years (odds ratio = 1.03, p = .01). All associations withstood adjustment for a range of possible confounders. Conclusions: The present analyses provide additional support for the hypothesis that it is low not high cardiac and cortisol stress reactivity that is related to adiposity. ",
author = "Anna Phillips and TJ Roseboom and Douglas Carroll and {De Rooij}, SR",
year = "2012",
doi = "10.1097/PSY.0b013e31825e3b91",
language = "English",
volume = "74",
pages = "699--710",
journal = "Psychosomatic Medicine",
issn = "0033-3174",
publisher = "Lippincott Williams and Wilkins",

}

RIS

TY - JOUR

T1 - Cardiovascular and cortisol reactions to acute psychological stress and adiposity: Cross-sectional and prospective associations in the Dutch Famine Birth Cohort Study.

AU - Phillips, Anna

AU - Roseboom, TJ

AU - Carroll, Douglas

AU - De Rooij, SR

PY - 2012

Y1 - 2012

N2 - Objective: In recent analyses of data from a large community sample, negative cross-sectional and prospective associations between cardiac stress reactivity and obesity were observed. The present study reexamined the association between cardiovascular reactivity and adiposity in the Dutch Famine Birth Cohort, with the additional aim of examining the association between cortisol reactivity and adiposity. Methods: Blood pressure, heart rate, and salivary cortisol were measured at rest and in response to standard laboratory stress tasks in 725 adults. Height, weight, waist-and-hip circumference, and skinfold thickness were measured. Between 4 to 7 years later, 460 participants reported current height and weight. Obesity was defined as a body mass index of 30 kg/m2 or higher. Results: Those with a greater body mass index (β = −0.39 beats per minute (bpm)), waist-to-hip ratio (β = −0.15 bpm), and triceps and subscapular skinfold thicknesses (β = −1.0 and −1.8 bpm) or who were categorized as obese (−3.9 bpm) displayed smaller cardiac reactions to acute stress (all p < .001). With the exception of waist-to-hip ratio, the same negative associations emerged for cortisol reactivity (all p ≤ .01). In prospective analyses, low cardiac reactivity was associated with an increased likelihood of becoming or remaining obese in the subsequent 4 to 7 years (odds ratio = 1.03, p = .01). All associations withstood adjustment for a range of possible confounders. Conclusions: The present analyses provide additional support for the hypothesis that it is low not high cardiac and cortisol stress reactivity that is related to adiposity.

AB - Objective: In recent analyses of data from a large community sample, negative cross-sectional and prospective associations between cardiac stress reactivity and obesity were observed. The present study reexamined the association between cardiovascular reactivity and adiposity in the Dutch Famine Birth Cohort, with the additional aim of examining the association between cortisol reactivity and adiposity. Methods: Blood pressure, heart rate, and salivary cortisol were measured at rest and in response to standard laboratory stress tasks in 725 adults. Height, weight, waist-and-hip circumference, and skinfold thickness were measured. Between 4 to 7 years later, 460 participants reported current height and weight. Obesity was defined as a body mass index of 30 kg/m2 or higher. Results: Those with a greater body mass index (β = −0.39 beats per minute (bpm)), waist-to-hip ratio (β = −0.15 bpm), and triceps and subscapular skinfold thicknesses (β = −1.0 and −1.8 bpm) or who were categorized as obese (−3.9 bpm) displayed smaller cardiac reactions to acute stress (all p < .001). With the exception of waist-to-hip ratio, the same negative associations emerged for cortisol reactivity (all p ≤ .01). In prospective analyses, low cardiac reactivity was associated with an increased likelihood of becoming or remaining obese in the subsequent 4 to 7 years (odds ratio = 1.03, p = .01). All associations withstood adjustment for a range of possible confounders. Conclusions: The present analyses provide additional support for the hypothesis that it is low not high cardiac and cortisol stress reactivity that is related to adiposity.

U2 - 10.1097/PSY.0b013e31825e3b91

DO - 10.1097/PSY.0b013e31825e3b91

M3 - Article

VL - 74

SP - 699

EP - 710

JO - Psychosomatic Medicine

JF - Psychosomatic Medicine

SN - 0033-3174

ER -