Cardiac autonomic neuropathy in patients with diabetes mellitus: Current perspectives

Victoria L. Fisher; Abd A. Tahrani

doi:10.2147/DMSO.S129797

Cardiac autonomic neuropathy in patients with diabetes mellitus: Current perspectives

Victoria L. Fisher, Abd A. Tahrani^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

40 Citations (Scopus)

275 Downloads (Pure)

Abstract

Cardiac autonomic neuropathy (CAN) is a common and often-underdiagnosed complication of diabetes mellitus (DM). CAN is associated with increased mortality, cardiovascular disease, chronic kidney disease, and morbidity in patients with DM, but despite these significant consequences CAN often remains undiagnosed for a prolonged period. This is commonly due to the disease being asymptomatic until the later stages, as well as a lack of easily available screening strategies. In this article, we review the latest developments in the epidemiology, pathogenesis, diagnosis, consequences, and treatments of CAN in patients with DM.

Original language	English
Pages (from-to)	419-434
Number of pages	16
Journal	Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Volume	10
DOIs	https://doi.org/10.2147/DMSO.S129797
Publication status	Published - 6 Oct 2017

Keywords

30:15 ratio
Autonomic
Cardiovascular
Deep breathing
Ewing criteria
Ewing tests
Heart-rate variability
Hyperglycemia
Neuropathy
Orthostatic hypotension
Parasympathetic
Postural hypotension
Sympathetic
Valsalva ratio

ASJC Scopus subject areas

Internal Medicine
Pharmacology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.2147/DMSO.S129797Licence: Creative Commons: Attribution-NonCommercial (CC BY-NC)

Fisher_&_Tahrani_Cardiac_autonomic_neuropathy_Diabetes_Metabolic_Syndrome_and_Obesity_Targets_and_Therapy_2017
Checked for eligibility: 09/01/2018
Final published version, 993 KBLicence: Creative Commons: Attribution-NonCommercial (CC BY-NC)

Cite this

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title = "Cardiac autonomic neuropathy in patients with diabetes mellitus: Current perspectives",

abstract = "Cardiac autonomic neuropathy (CAN) is a common and often-underdiagnosed complication of diabetes mellitus (DM). CAN is associated with increased mortality, cardiovascular disease, chronic kidney disease, and morbidity in patients with DM, but despite these significant consequences CAN often remains undiagnosed for a prolonged period. This is commonly due to the disease being asymptomatic until the later stages, as well as a lack of easily available screening strategies. In this article, we review the latest developments in the epidemiology, pathogenesis, diagnosis, consequences, and treatments of CAN in patients with DM.",

keywords = "30:15 ratio, Autonomic, Cardiovascular, Deep breathing, Ewing criteria, Ewing tests, Heart-rate variability, Hyperglycemia, Neuropathy, Orthostatic hypotension, Parasympathetic, Postural hypotension, Sympathetic, Valsalva ratio",

author = "Fisher, {Victoria L.} and Tahrani, {Abd A.}",

year = "2017",

month = oct,

day = "6",

doi = "10.2147/DMSO.S129797",

language = "English",

volume = "10",

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journal = "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy",

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T1 - Cardiac autonomic neuropathy in patients with diabetes mellitus

T2 - Current perspectives

AU - Fisher, Victoria L.

AU - Tahrani, Abd A.

PY - 2017/10/6

Y1 - 2017/10/6

N2 - Cardiac autonomic neuropathy (CAN) is a common and often-underdiagnosed complication of diabetes mellitus (DM). CAN is associated with increased mortality, cardiovascular disease, chronic kidney disease, and morbidity in patients with DM, but despite these significant consequences CAN often remains undiagnosed for a prolonged period. This is commonly due to the disease being asymptomatic until the later stages, as well as a lack of easily available screening strategies. In this article, we review the latest developments in the epidemiology, pathogenesis, diagnosis, consequences, and treatments of CAN in patients with DM.

AB - Cardiac autonomic neuropathy (CAN) is a common and often-underdiagnosed complication of diabetes mellitus (DM). CAN is associated with increased mortality, cardiovascular disease, chronic kidney disease, and morbidity in patients with DM, but despite these significant consequences CAN often remains undiagnosed for a prolonged period. This is commonly due to the disease being asymptomatic until the later stages, as well as a lack of easily available screening strategies. In this article, we review the latest developments in the epidemiology, pathogenesis, diagnosis, consequences, and treatments of CAN in patients with DM.

KW - 30:15 ratio

KW - Autonomic

KW - Cardiovascular

KW - Deep breathing

KW - Ewing criteria

KW - Ewing tests

KW - Heart-rate variability

KW - Hyperglycemia

KW - Neuropathy

KW - Orthostatic hypotension

KW - Parasympathetic

KW - Postural hypotension

KW - Sympathetic

KW - Valsalva ratio

U2 - 10.2147/DMSO.S129797

DO - 10.2147/DMSO.S129797

M3 - Review article

AN - SCOPUS:85032853501

SN - 1178-7007

VL - 10

SP - 419

EP - 434

JO - Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy

JF - Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy

ER -

Cardiac autonomic neuropathy in patients with diabetes mellitus: Current perspectives

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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