Carbapenem and colistin resistance in Enterobacter: determinants and clones

Research output: Contribution to journalArticlepeer-review

Authors

Colleges, School and Institutes

Abstract

Enterobacter is a globally important pathogen. Here we clarify its taxonomy and review recent developments in its resistance to carbapenem and colistin, illustrating that Enterobacter has a large arsenal of mechanisms to grow under antimicrobial pressure. Further studies are required to decipher colistin heteroresistance and understand why certain Enterobacter lineages have emerged clinically.

Bibliographic note

Funding Information: Relevant research works of the author are supported by grants from the National Natural Science Foundation of China (project no. 81772233 , 81661130159 and 81861138055 ), West China Hospital of Sichuan University (1.3.5 project for disciplines of excellence, project no. ZYYC08006 ; and grant no. 312190022 ), the Newton Advanced Fellowship, Royal Society, UK ( NA150363 ), and the Medical Research Council ( MR/S013660/1 ).

Details

Original languageEnglish
Pages (from-to)473-476
Number of pages4
JournalTrends in Microbiology
Volume29
Issue number6
Early online date8 Jan 2021
Publication statusPublished - Jun 2021

Keywords

  • Enterobacter, antimicrobial resistance, carbapenem resistance, colistin resistance, high-risk lineages, taxonomy

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