Can metabolomic profiling predict response to therapy?

Catherine Mary McGrath; Stephen Young

doi:10.1038/s41584-018-0136-z

Can metabolomic profiling predict response to therapy?

Catherine Mary McGrath, Stephen Young

Inflammation and Ageing

Research output: Contribution to journal › Comment/debate

2 Citations (Scopus)

238 Downloads (Pure)

Abstract

Shifts in cellular metabolism are central to activation, differentiation and proliferation of inflammatory cells and can contribute to the pathogenesis of inflammatory diseases. Integrating metabolomics data with other omics data is a major challenge but might enable clinicians to stratify stages of disease and response to therapy in patients with rheumatoid arthritis.

Original language	English
Journal	Nature Reviews Rheumatology
DOIs	https://doi.org/10.1038/s41584-018-0136-z
Publication status	Published - 7 Dec 2018

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10.1038/s41584-018-0136-zLicence: None: All rights reserved

Young NV Author Accepted
First published in Nature Reviews Rheumatology (2018), McGrath et al, Can metabolomic profiling predict response to therapy? https://doi.org/10.1038/s41584-018-0136-z
Accepted author manuscript, 160 KBLicence: None: All rights reserved

https://www.nature.com/articles/s41584-018-0136-zLicence: None: All rights reserved

Cite this

@article{8369929843894f4f87fd3c200a8d3585,

title = "Can metabolomic profiling predict response to therapy?",

abstract = "Shifts in cellular metabolism are central to activation, differentiation and proliferation of inflammatory cells and can contribute to the pathogenesis of inflammatory diseases. Integrating metabolomics data with other omics data is a major challenge but might enable clinicians to stratify stages of disease and response to therapy in patients with rheumatoid arthritis.",

author = "McGrath, {Catherine Mary} and Stephen Young",

year = "2018",

month = dec,

day = "7",

doi = "10.1038/s41584-018-0136-z",

language = "English",

journal = "Nature Reviews Rheumatology",