Brief Report: A Longitudinal Study of Excessive Smiling and Laughing in Children with Angelman Syndrome

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Brief Report : A Longitudinal Study of Excessive Smiling and Laughing in Children with Angelman Syndrome. / Adams, Dawn; Horsler, Kate; Mount, Rebecca; Oliver, Chris.

In: Journal of Autism and Developmental Disorders, Vol. 45, No. 8, 08.2015, p. 2624-2627.

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@article{285285fa46794e829f9199a7076c7c74,
title = "Brief Report: A Longitudinal Study of Excessive Smiling and Laughing in Children with Angelman Syndrome",
abstract = "Elevated laughing and smiling is a key characteristic of the Angelman syndrome behavioral phenotype, with cross-sectional studies reporting changes with environment and age. This study compares levels of laughing and smiling in 12 participants across three experimental conditions [full social interaction (with eye contact), social interaction with no eye contact, proximity only] at two data points. No differences were noted in frequency of laughing and smiling over time in any condition. However, with age as a covariate, the frequency of laughing and smiling decreased over time in the full social interaction (with eye contact) condition only. As this is the first longitudinal study to explore these behaviors in Angelman syndrome, the results suggest a gene-environment-time interaction within the behavioral phenotype.",
keywords = "Aging, Angelman syndrome, Behavior, Behavioral phenotype, Intellectual disability",
author = "Dawn Adams and Kate Horsler and Rebecca Mount and Chris Oliver",
note = "Export Date: 23 March 2015 Article in Press CODEN: JADDD Correspondence Address: Adams, D.; Cerebra Centre for Neurodevelopmental Disorders, School of Psychology, University of Birmingham, United Kingdom",
year = "2015",
month = aug,
doi = "10.1007/s10803-015-2404-y",
language = "English",
volume = "45",
pages = "2624--2627",
journal = "Journal of Autism and Developmental Disorders",
issn = "0162-3257",
publisher = "Springer",
number = "8",

}

RIS

TY - JOUR

T1 - Brief Report

T2 - A Longitudinal Study of Excessive Smiling and Laughing in Children with Angelman Syndrome

AU - Adams, Dawn

AU - Horsler, Kate

AU - Mount, Rebecca

AU - Oliver, Chris

N1 - Export Date: 23 March 2015 Article in Press CODEN: JADDD Correspondence Address: Adams, D.; Cerebra Centre for Neurodevelopmental Disorders, School of Psychology, University of Birmingham, United Kingdom

PY - 2015/8

Y1 - 2015/8

N2 - Elevated laughing and smiling is a key characteristic of the Angelman syndrome behavioral phenotype, with cross-sectional studies reporting changes with environment and age. This study compares levels of laughing and smiling in 12 participants across three experimental conditions [full social interaction (with eye contact), social interaction with no eye contact, proximity only] at two data points. No differences were noted in frequency of laughing and smiling over time in any condition. However, with age as a covariate, the frequency of laughing and smiling decreased over time in the full social interaction (with eye contact) condition only. As this is the first longitudinal study to explore these behaviors in Angelman syndrome, the results suggest a gene-environment-time interaction within the behavioral phenotype.

AB - Elevated laughing and smiling is a key characteristic of the Angelman syndrome behavioral phenotype, with cross-sectional studies reporting changes with environment and age. This study compares levels of laughing and smiling in 12 participants across three experimental conditions [full social interaction (with eye contact), social interaction with no eye contact, proximity only] at two data points. No differences were noted in frequency of laughing and smiling over time in any condition. However, with age as a covariate, the frequency of laughing and smiling decreased over time in the full social interaction (with eye contact) condition only. As this is the first longitudinal study to explore these behaviors in Angelman syndrome, the results suggest a gene-environment-time interaction within the behavioral phenotype.

KW - Aging

KW - Angelman syndrome

KW - Behavior

KW - Behavioral phenotype

KW - Intellectual disability

UR - http://www.scopus.com/inward/record.url?scp=84937971712&partnerID=8YFLogxK

U2 - 10.1007/s10803-015-2404-y

DO - 10.1007/s10803-015-2404-y

M3 - Article

C2 - 25749713

VL - 45

SP - 2624

EP - 2627

JO - Journal of Autism and Developmental Disorders

JF - Journal of Autism and Developmental Disorders

SN - 0162-3257

IS - 8

ER -