Brief Report: A Longitudinal Study of Excessive Smiling and Laughing in Children with Angelman Syndrome

Research output: Contribution to journalArticle

Authors

Colleges, School and Institutes

External organisations

  • Cerebra Centre for Neurodevelopmental Disorders

Abstract

Elevated laughing and smiling is a key characteristic of the Angelman syndrome behavioral phenotype, with cross-sectional studies reporting changes with environment and age. This study compares levels of laughing and smiling in 12 participants across three experimental conditions [full social interaction (with eye contact), social interaction with no eye contact, proximity only] at two data points. No differences were noted in frequency of laughing and smiling over time in any condition. However, with age as a covariate, the frequency of laughing and smiling decreased over time in the full social interaction (with eye contact) condition only. As this is the first longitudinal study to explore these behaviors in Angelman syndrome, the results suggest a gene-environment-time interaction within the behavioral phenotype.

Bibliographic note

Export Date: 23 March 2015 Article in Press CODEN: JADDD Correspondence Address: Adams, D.; Cerebra Centre for Neurodevelopmental Disorders, School of Psychology, University of Birmingham, United Kingdom

Details

Original languageEnglish
Pages (from-to)2624-2627
Number of pages4
JournalJournal of Autism and Developmental Disorders
Volume45
Issue number8
Early online date7 Mar 2015
Publication statusPublished - Aug 2015

Keywords

  • Aging, Angelman syndrome, Behavior, Behavioral phenotype, Intellectual disability