Abstract
Elevated laughing and smiling is a key characteristic of the Angelman syndrome behavioral phenotype, with cross-sectional studies reporting changes with environment and age. This study compares levels of laughing and smiling in 12 participants across three experimental conditions [full social interaction (with eye contact), social interaction with no eye contact, proximity only] at two data points. No differences were noted in frequency of laughing and smiling over time in any condition. However, with age as a covariate, the frequency of laughing and smiling decreased over time in the full social interaction (with eye contact) condition only. As this is the first longitudinal study to explore these behaviors in Angelman syndrome, the results suggest a gene-environment-time interaction within the behavioral phenotype.
| Original language | English |
|---|---|
| Pages (from-to) | 2624-2627 |
| Number of pages | 4 |
| Journal | Journal of Autism and Developmental Disorders |
| Volume | 45 |
| Issue number | 8 |
| Early online date | 7 Mar 2015 |
| DOIs | |
| Publication status | Published - Aug 2015 |
Bibliographical note
Export Date: 23 March 2015Article in Press
CODEN: JADDD
Correspondence Address: Adams, D.; Cerebra Centre for Neurodevelopmental Disorders, School of Psychology, University of Birmingham, United Kingdom
Keywords
- Aging
- Angelman syndrome
- Behavior
- Behavioral phenotype
- Intellectual disability
ASJC Scopus subject areas
- Developmental and Educational Psychology