Brain activation patterns during measurement of sub- and supra-second intervals

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Brain activation patterns during measurement of sub- and supra-second intervals. / Lewis, P. A.; Miall, R. C.

In: Neuropsychologia, Vol. 41, No. 12, 01.01.2003, p. 1583-1592.

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@article{849ab3de4a2f4d519d8357d9421d8d15,
title = "Brain activation patterns during measurement of sub- and supra-second intervals",
abstract = "The possibility that different neural systems are used to measure temporal durations at the sub-second and several second ranges has been supported by pharmacological manipulation, psychophysics, and neural network modelling. Here, we add to this literature by using fMRI to isolate differences between the brain networks which measure 0.6 and 3s in a temporal discrimination task with visual discrimination for control. We observe activity in bilateral insula and dorsolateral prefrontal cortex, and in right hemispheric pre-supplementary motor area, frontal pole, and inferior parietal cortex during measurement of both intervals, suggesting that these regions constitute a system used in temporal discrimination at both ranges. The frontal operculum, left cerebellar hemisphere and middle and superior temporal gyri, all show significantly greater activity during measurement of the shorter interval, supporting the hypotheses that the motor system is preferentially involved in the measurement of sub-second intervals, and that auditory imagery is preferentially used during measurement of the same. Only a few voxels, falling in the left posterior cingulate and inferior parietal lobe, are more active in the 3s condition. Overall, this study shows that although many brain regions are used for the measurement of both sub- and supra-second temporal durations, there are also differences in activation patterns, suggesting that distinct components are used for the two durations.",
keywords = "FMRI, Motor system, Neural clock, Time measurement, Time perception, Timing",
author = "Lewis, {P. A.} and Miall, {R. C.}",
year = "2003",
month = jan,
day = "1",
doi = "10.1016/S0028-3932(03)00118-0",
language = "English",
volume = "41",
pages = "1583--1592",
journal = "Neuropsychologia",
issn = "0028-3932",
publisher = "Elsevier",
number = "12",

}

RIS

TY - JOUR

T1 - Brain activation patterns during measurement of sub- and supra-second intervals

AU - Lewis, P. A.

AU - Miall, R. C.

PY - 2003/1/1

Y1 - 2003/1/1

N2 - The possibility that different neural systems are used to measure temporal durations at the sub-second and several second ranges has been supported by pharmacological manipulation, psychophysics, and neural network modelling. Here, we add to this literature by using fMRI to isolate differences between the brain networks which measure 0.6 and 3s in a temporal discrimination task with visual discrimination for control. We observe activity in bilateral insula and dorsolateral prefrontal cortex, and in right hemispheric pre-supplementary motor area, frontal pole, and inferior parietal cortex during measurement of both intervals, suggesting that these regions constitute a system used in temporal discrimination at both ranges. The frontal operculum, left cerebellar hemisphere and middle and superior temporal gyri, all show significantly greater activity during measurement of the shorter interval, supporting the hypotheses that the motor system is preferentially involved in the measurement of sub-second intervals, and that auditory imagery is preferentially used during measurement of the same. Only a few voxels, falling in the left posterior cingulate and inferior parietal lobe, are more active in the 3s condition. Overall, this study shows that although many brain regions are used for the measurement of both sub- and supra-second temporal durations, there are also differences in activation patterns, suggesting that distinct components are used for the two durations.

AB - The possibility that different neural systems are used to measure temporal durations at the sub-second and several second ranges has been supported by pharmacological manipulation, psychophysics, and neural network modelling. Here, we add to this literature by using fMRI to isolate differences between the brain networks which measure 0.6 and 3s in a temporal discrimination task with visual discrimination for control. We observe activity in bilateral insula and dorsolateral prefrontal cortex, and in right hemispheric pre-supplementary motor area, frontal pole, and inferior parietal cortex during measurement of both intervals, suggesting that these regions constitute a system used in temporal discrimination at both ranges. The frontal operculum, left cerebellar hemisphere and middle and superior temporal gyri, all show significantly greater activity during measurement of the shorter interval, supporting the hypotheses that the motor system is preferentially involved in the measurement of sub-second intervals, and that auditory imagery is preferentially used during measurement of the same. Only a few voxels, falling in the left posterior cingulate and inferior parietal lobe, are more active in the 3s condition. Overall, this study shows that although many brain regions are used for the measurement of both sub- and supra-second temporal durations, there are also differences in activation patterns, suggesting that distinct components are used for the two durations.

KW - FMRI

KW - Motor system

KW - Neural clock

KW - Time measurement

KW - Time perception

KW - Timing

UR - http://www.scopus.com/inward/record.url?scp=0042845807&partnerID=8YFLogxK

U2 - 10.1016/S0028-3932(03)00118-0

DO - 10.1016/S0028-3932(03)00118-0

M3 - Article

C2 - 12887983

AN - SCOPUS:0042845807

VL - 41

SP - 1583

EP - 1592

JO - Neuropsychologia

JF - Neuropsychologia

SN - 0028-3932

IS - 12

ER -