Boric acid as an adjunct to periodontal therapy: A systematic review and meta-analysis

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Boric acid as an adjunct to periodontal therapy : A systematic review and meta-analysis. / Bashir, Nasir Zeeshan; Krstic, Milan.

In: International Journal of Dental Hygiene, 29.01.2021.

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@article{db5933c110be420883d713b91abe0feb,
title = "Boric acid as an adjunct to periodontal therapy: A systematic review and meta-analysis",
abstract = "OBJECTIVE: To evaluate the efficacy of boric acid as an adjunct to non-surgical periodontal therapy, in comparison with a placebo adjunct, in terms of changes in probing pocket depth (PPD) and clinical attachment level (CAL), in patients with periodontitis.METHODS: Four electronic databases were searched from inception to May 2020 (PubMed, Cochrane CENTRAL, EMBASE via OVID and Web of Science). Clinical outcomes were extracted, pooled and meta-analyses conducted using mean difference with standard deviations.RESULTS: For PPD, a mean additional reduction of 0.58 mm (95% CI: -0.03-1.19 mm, p = 0.06) was observed at 3 months and a mean additional reduction of 1.18 mm (95% CI: 0.97-1.40 mm, p < 0.05) at 6 months, compared with placebo. For CAL, a mean additional gain of 0.62 mm (95% CI: -0.07-1.32 mm, p = 0.08) was observed at 3 months and a mean additional gain of 1.24 mm (95% CI: 0.89-1.58 mm, p < 0.05) at 6 months, compared with placebo. No adverse events were reported in any studies.CONCLUSIONS: The adjunctive use of boric acid in non-surgical periodontal therapy results in improved treatment outcomes at 3 and 6 months, with no adverse events reported.",
keywords = "boric acid, meta‐analysis, outcomes, periodontitis, scaling and root planing, systematic review",
author = "Bashir, {Nasir Zeeshan} and Milan Krstic",
note = "{\textcopyright} 2021 The Authors. International Journal of Dental Hygiene published by John Wiley & Sons Ltd.",
year = "2021",
month = jan,
day = "29",
doi = "10.1111/idh.12487",
language = "English",
journal = "International Journal of Dental Hygiene",
issn = "1601-5029",
publisher = "Wiley",

}

RIS

TY - JOUR

T1 - Boric acid as an adjunct to periodontal therapy

T2 - A systematic review and meta-analysis

AU - Bashir, Nasir Zeeshan

AU - Krstic, Milan

N1 - © 2021 The Authors. International Journal of Dental Hygiene published by John Wiley & Sons Ltd.

PY - 2021/1/29

Y1 - 2021/1/29

N2 - OBJECTIVE: To evaluate the efficacy of boric acid as an adjunct to non-surgical periodontal therapy, in comparison with a placebo adjunct, in terms of changes in probing pocket depth (PPD) and clinical attachment level (CAL), in patients with periodontitis.METHODS: Four electronic databases were searched from inception to May 2020 (PubMed, Cochrane CENTRAL, EMBASE via OVID and Web of Science). Clinical outcomes were extracted, pooled and meta-analyses conducted using mean difference with standard deviations.RESULTS: For PPD, a mean additional reduction of 0.58 mm (95% CI: -0.03-1.19 mm, p = 0.06) was observed at 3 months and a mean additional reduction of 1.18 mm (95% CI: 0.97-1.40 mm, p < 0.05) at 6 months, compared with placebo. For CAL, a mean additional gain of 0.62 mm (95% CI: -0.07-1.32 mm, p = 0.08) was observed at 3 months and a mean additional gain of 1.24 mm (95% CI: 0.89-1.58 mm, p < 0.05) at 6 months, compared with placebo. No adverse events were reported in any studies.CONCLUSIONS: The adjunctive use of boric acid in non-surgical periodontal therapy results in improved treatment outcomes at 3 and 6 months, with no adverse events reported.

AB - OBJECTIVE: To evaluate the efficacy of boric acid as an adjunct to non-surgical periodontal therapy, in comparison with a placebo adjunct, in terms of changes in probing pocket depth (PPD) and clinical attachment level (CAL), in patients with periodontitis.METHODS: Four electronic databases were searched from inception to May 2020 (PubMed, Cochrane CENTRAL, EMBASE via OVID and Web of Science). Clinical outcomes were extracted, pooled and meta-analyses conducted using mean difference with standard deviations.RESULTS: For PPD, a mean additional reduction of 0.58 mm (95% CI: -0.03-1.19 mm, p = 0.06) was observed at 3 months and a mean additional reduction of 1.18 mm (95% CI: 0.97-1.40 mm, p < 0.05) at 6 months, compared with placebo. For CAL, a mean additional gain of 0.62 mm (95% CI: -0.07-1.32 mm, p = 0.08) was observed at 3 months and a mean additional gain of 1.24 mm (95% CI: 0.89-1.58 mm, p < 0.05) at 6 months, compared with placebo. No adverse events were reported in any studies.CONCLUSIONS: The adjunctive use of boric acid in non-surgical periodontal therapy results in improved treatment outcomes at 3 and 6 months, with no adverse events reported.

KW - boric acid

KW - meta‐analysis

KW - outcomes

KW - periodontitis

KW - scaling and root planing

KW - systematic review

U2 - 10.1111/idh.12487

DO - 10.1111/idh.12487

M3 - Article

C2 - 33513275

JO - International Journal of Dental Hygiene

JF - International Journal of Dental Hygiene

SN - 1601-5029

ER -