Biotinylated boronic acid fluorophore conjugates: Quencher elimination strategy for imaging and saccharide detection

Research output: Contribution to journalArticle

Authors

  • F D'Hooge
  • SA Elfeky
  • SE Flower
  • SI Pascu
  • ATA Jenkins
  • JMH van den Elsen
  • TD James

Colleges, School and Institutes

Abstract

A biotinylated boronic acid fluorophore conjugate bound to a diol-quencher via a boronic ester linkage demonstrated a fluorescence increase upon exposure to model saccharides. The sensing motif was attached to SuperAvidin microspheres where the sensing regime was imaged by fluorescence microscopy.

Details

Original languageEnglish
Pages (from-to)3274-3280
Number of pages7
JournalRSC Advances
Volume2
Issue number8
Publication statusPublished - 1 Jan 2012