Beta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle does not modulate disease severity in the rodent meniscectomy model of osteoarthritis

D P Tonge; Simon Jones; T Parr; R Bardsley; M Doherty; R A Maciewicz

doi:10.1016/j.joca.2009.11.014

Beta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle does not modulate disease severity in the rodent meniscectomy model of osteoarthritis

D P Tonge, Simon Jones, T Parr, R Bardsley, M Doherty, R A Maciewicz

Immunology and Immunotherapy

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

To examine whether beta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle can modulate the severity of osteoarthritis (OA) in the rodent meniscectomy (MNX) model.

Original language	English
Pages (from-to)	555-62
Number of pages	8
Journal	Osteoarthritis and Cartilage
Volume	18
Issue number	4
DOIs	https://doi.org/10.1016/j.joca.2009.11.014
Publication status	Published - Apr 2010

Bibliographical note

Keywords

Animals
Quadriceps Muscle
Rats, Inbred Lew
Adrenergic beta-Agonists
Osteoarthritis
Disease Models, Animal
Weight-Bearing
Clenbuterol
Muscle, Skeletal
Body Weight
Rats
Hypertrophy
Myosin Heavy Chains
Male

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10.1016/j.joca.2009.11.014

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title = "Beta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle does not modulate disease severity in the rodent meniscectomy model of osteoarthritis",

abstract = "To examine whether beta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle can modulate the severity of osteoarthritis (OA) in the rodent meniscectomy (MNX) model.",

keywords = "Animals, Quadriceps Muscle, Rats, Inbred Lew, Adrenergic beta-Agonists, Osteoarthritis, Disease Models, Animal, Weight-Bearing, Clenbuterol, Muscle, Skeletal, Body Weight, Rats, Hypertrophy, Myosin Heavy Chains, Male",

author = "Tonge, {D P} and Simon Jones and T Parr and R Bardsley and M Doherty and Maciewicz, {R A}",

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AU - Tonge, D P

AU - Jones, Simon

AU - Parr, T

AU - Bardsley, R

AU - Doherty, M

AU - Maciewicz, R A

PY - 2010/4

Y1 - 2010/4

N2 - To examine whether beta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle can modulate the severity of osteoarthritis (OA) in the rodent meniscectomy (MNX) model.

AB - To examine whether beta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle can modulate the severity of osteoarthritis (OA) in the rodent meniscectomy (MNX) model.

KW - Animals

KW - Quadriceps Muscle

KW - Rats, Inbred Lew

KW - Adrenergic beta-Agonists

KW - Osteoarthritis

KW - Disease Models, Animal

KW - Weight-Bearing

KW - Clenbuterol

KW - Muscle, Skeletal

KW - Body Weight

KW - Rats

KW - Hypertrophy

KW - Myosin Heavy Chains

KW - Male

U2 - 10.1016/j.joca.2009.11.014

DO - 10.1016/j.joca.2009.11.014

M3 - Article

C2 - 20060953

SN - 1522-9653

VL - 18

SP - 555

EP - 562

JO - Osteoarthritis and Cartilage

JF - Osteoarthritis and Cartilage

IS - 4

ER -

Beta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle does not modulate disease severity in the rodent meniscectomy model of osteoarthritis

Abstract

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Keywords

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