Behaviour in Cornelia de Lange syndrome: A systematic review

Research output: Contribution to journalArticle

Standard

Behaviour in Cornelia de Lange syndrome : A systematic review. / Mulder, Paul A.; Huisman, Sylvia A.; Hennekam, Raoul C.; Oliver, Chris; van Balkom, Ingrid D C; Piening, Sigrid.

In: Developmental Medicine and Child Neurology, Vol. 59, No. 4, 04.2017, p. 361-366.

Research output: Contribution to journalArticle

Harvard

Mulder, PA, Huisman, SA, Hennekam, RC, Oliver, C, van Balkom, IDC & Piening, S 2017, 'Behaviour in Cornelia de Lange syndrome: A systematic review', Developmental Medicine and Child Neurology, vol. 59, no. 4, pp. 361-366. https://doi.org/10.1111/dmcn.13361

APA

Mulder, P. A., Huisman, S. A., Hennekam, R. C., Oliver, C., van Balkom, I. D. C., & Piening, S. (2017). Behaviour in Cornelia de Lange syndrome: A systematic review. Developmental Medicine and Child Neurology, 59(4), 361-366. https://doi.org/10.1111/dmcn.13361

Vancouver

Author

Mulder, Paul A. ; Huisman, Sylvia A. ; Hennekam, Raoul C. ; Oliver, Chris ; van Balkom, Ingrid D C ; Piening, Sigrid. / Behaviour in Cornelia de Lange syndrome : A systematic review. In: Developmental Medicine and Child Neurology. 2017 ; Vol. 59, No. 4. pp. 361-366.

Bibtex

@article{3c7e7fc3f80d4a16a7263472cd305594,
title = "Behaviour in Cornelia de Lange syndrome: A systematic review",
abstract = "Aim: Careful study and accurate description of behaviour are important to understand developmental challenges for individuals with Cornelia de Lange syndrome (CdLS). Here we present a systematic review of current understanding of behaviour in CdLS. Method: A systematic search was performed for articles published between January 1946 and December 2015 evaluating autism, self-injury, and/or cognition in CdLS. After study-selection, 43 papers were included. The Cochrane quality criteria were adjusted to assign quality scores to the included studies. Results: Participants were mostly categorized in the severe/profound developmental level. Methodology and quality were very heterogeneous, as well as reporting occurrence of autism. Self-injurious behaviour was reported in 15 papers. Physical conditions were reported in 21 studies, mostly related to hearing and vision. Only nine studies mentioned details about medication. Interpretation: Comparison of presented results was hindered by heterogeneous assessment methods. Improving our understanding of behavioural characteristics in CdLS requires more uniform methodology. We propose a criterion standard of instruments that can ideally be used in assessment of behaviour and development. This will improve understanding of behaviour in the context of developmental level and daily functioning.",
author = "Mulder, {Paul A.} and Huisman, {Sylvia A.} and Hennekam, {Raoul C.} and Chris Oliver and {van Balkom}, {Ingrid D C} and Sigrid Piening",
year = "2017",
month = "4",
doi = "10.1111/dmcn.13361",
language = "English",
volume = "59",
pages = "361--366",
journal = "Developmental Medicine and Child Neurology",
issn = "0012-1622",
publisher = "Wiley",
number = "4",

}

RIS

TY - JOUR

T1 - Behaviour in Cornelia de Lange syndrome

T2 - A systematic review

AU - Mulder, Paul A.

AU - Huisman, Sylvia A.

AU - Hennekam, Raoul C.

AU - Oliver, Chris

AU - van Balkom, Ingrid D C

AU - Piening, Sigrid

PY - 2017/4

Y1 - 2017/4

N2 - Aim: Careful study and accurate description of behaviour are important to understand developmental challenges for individuals with Cornelia de Lange syndrome (CdLS). Here we present a systematic review of current understanding of behaviour in CdLS. Method: A systematic search was performed for articles published between January 1946 and December 2015 evaluating autism, self-injury, and/or cognition in CdLS. After study-selection, 43 papers were included. The Cochrane quality criteria were adjusted to assign quality scores to the included studies. Results: Participants were mostly categorized in the severe/profound developmental level. Methodology and quality were very heterogeneous, as well as reporting occurrence of autism. Self-injurious behaviour was reported in 15 papers. Physical conditions were reported in 21 studies, mostly related to hearing and vision. Only nine studies mentioned details about medication. Interpretation: Comparison of presented results was hindered by heterogeneous assessment methods. Improving our understanding of behavioural characteristics in CdLS requires more uniform methodology. We propose a criterion standard of instruments that can ideally be used in assessment of behaviour and development. This will improve understanding of behaviour in the context of developmental level and daily functioning.

AB - Aim: Careful study and accurate description of behaviour are important to understand developmental challenges for individuals with Cornelia de Lange syndrome (CdLS). Here we present a systematic review of current understanding of behaviour in CdLS. Method: A systematic search was performed for articles published between January 1946 and December 2015 evaluating autism, self-injury, and/or cognition in CdLS. After study-selection, 43 papers were included. The Cochrane quality criteria were adjusted to assign quality scores to the included studies. Results: Participants were mostly categorized in the severe/profound developmental level. Methodology and quality were very heterogeneous, as well as reporting occurrence of autism. Self-injurious behaviour was reported in 15 papers. Physical conditions were reported in 21 studies, mostly related to hearing and vision. Only nine studies mentioned details about medication. Interpretation: Comparison of presented results was hindered by heterogeneous assessment methods. Improving our understanding of behavioural characteristics in CdLS requires more uniform methodology. We propose a criterion standard of instruments that can ideally be used in assessment of behaviour and development. This will improve understanding of behaviour in the context of developmental level and daily functioning.

UR - http://www.scopus.com/inward/record.url?scp=85006814748&partnerID=8YFLogxK

U2 - 10.1111/dmcn.13361

DO - 10.1111/dmcn.13361

M3 - Article

AN - SCOPUS:85006814748

VL - 59

SP - 361

EP - 366

JO - Developmental Medicine and Child Neurology

JF - Developmental Medicine and Child Neurology

SN - 0012-1622

IS - 4

ER -