Azetidines and their applications in asymmetric catalysis

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Azetidines and their applications in asymmetric catalysis. / Milton, Joseph P.; Fossey, John S.

In: Tetrahedron, Vol. 77, 131767, 01.01.2021.

Research output: Contribution to journalReview articlepeer-review

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@article{0994e397c66c487fb20ea33aeef83b76,
title = "Azetidines and their applications in asymmetric catalysis",
abstract = "Since the early 1990s asymmetric catalytic applications of chiral, azetidine-derived, ligands and organocatalysts have been developed and utilised to engender asymmetry in reactions including Friedel-Crafts alkylations, Henry reactions and Michael-type reactions. This review surveys the effective synthetic opportunities presented by chiral azetidines in asymmetric catalysis. In order to benchmark, contrast and evaluate these asymmetric azetidine-containing catalysts, comparisons with aziridine- and pyrrolidine-containing analogues are drawn.",
keywords = "Asymmetric catalysis, AzePhenol, Azetidines, Aziridines, ProPhenol, Pyrrolidines",
author = "Milton, {Joseph P.} and Fossey, {John S.}",
note = "Funding Information: JPM and JSF would like to thank the University of Birmingham for support. JPM and JSF thank members of our research group for assistance in the latter stages of manuscript preparation. Publisher Copyright: {\textcopyright} 2020 Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "2021",
month = jan,
day = "1",
doi = "10.1016/j.tet.2020.131767",
language = "English",
volume = "77",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Azetidines and their applications in asymmetric catalysis

AU - Milton, Joseph P.

AU - Fossey, John S.

N1 - Funding Information: JPM and JSF would like to thank the University of Birmingham for support. JPM and JSF thank members of our research group for assistance in the latter stages of manuscript preparation. Publisher Copyright: © 2020 Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Since the early 1990s asymmetric catalytic applications of chiral, azetidine-derived, ligands and organocatalysts have been developed and utilised to engender asymmetry in reactions including Friedel-Crafts alkylations, Henry reactions and Michael-type reactions. This review surveys the effective synthetic opportunities presented by chiral azetidines in asymmetric catalysis. In order to benchmark, contrast and evaluate these asymmetric azetidine-containing catalysts, comparisons with aziridine- and pyrrolidine-containing analogues are drawn.

AB - Since the early 1990s asymmetric catalytic applications of chiral, azetidine-derived, ligands and organocatalysts have been developed and utilised to engender asymmetry in reactions including Friedel-Crafts alkylations, Henry reactions and Michael-type reactions. This review surveys the effective synthetic opportunities presented by chiral azetidines in asymmetric catalysis. In order to benchmark, contrast and evaluate these asymmetric azetidine-containing catalysts, comparisons with aziridine- and pyrrolidine-containing analogues are drawn.

KW - Asymmetric catalysis

KW - AzePhenol

KW - Azetidines

KW - Aziridines

KW - ProPhenol

KW - Pyrrolidines

UR - http://www.scopus.com/inward/record.url?scp=85097098137&partnerID=8YFLogxK

U2 - 10.1016/j.tet.2020.131767

DO - 10.1016/j.tet.2020.131767

M3 - Review article

AN - SCOPUS:85097098137

VL - 77

JO - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

M1 - 131767

ER -