Azetidines and their applications in asymmetric catalysis

Research output: Contribution to journalReview articlepeer-review

Authors

Colleges, School and Institutes

Abstract

Since the early 1990s asymmetric catalytic applications of chiral, azetidine-derived, ligands and organocatalysts have been developed and utilised to engender asymmetry in reactions including Friedel-Crafts alkylations, Henry reactions and Michael-type reactions. This review surveys the effective synthetic opportunities presented by chiral azetidines in asymmetric catalysis. In order to benchmark, contrast and evaluate these asymmetric azetidine-containing catalysts, comparisons with aziridine- and pyrrolidine-containing analogues are drawn.

Bibliographic note

Funding Information: JPM and JSF would like to thank the University of Birmingham for support. JPM and JSF thank members of our research group for assistance in the latter stages of manuscript preparation. Publisher Copyright: © 2020 Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

Details

Original languageEnglish
Article number131767
JournalTetrahedron
Volume77
Early online date18 Nov 2020
Publication statusPublished - 1 Jan 2021

Keywords

  • Asymmetric catalysis, AzePhenol, Azetidines, Aziridines, ProPhenol, Pyrrolidines

ASJC Scopus subject areas