Asymmetric Synthesis of cis-3,4-Dihydrocoumarins via [4 + 2] Cycloadditions Catalyzed by Amidine Derivatives
Research output: Contribution to journal › Article
Colleges, School and Institutes
- State Key Laboratory of Bioreactor Engineering & Department of Chemistry, East China University of Science and Technology, Shanghai 200237, China.
A highly efficient chiral amidine derivative-catalyzed tandem Michael addition/lactonization of carboxylic acids and o-quinone methides (o-QMs) has been developed that enables the asymmetric synthesis of cis-3,4-dihydrocoumarins bearing contiguous tertiary stereogenic centers in high yields with excellent stereoselectivities.
|Number of pages||9|
|Journal||Journal of Organic Chemistry|
|Early online date||25 Apr 2017|
|Publication status||Published - 19 May 2017|