Association between chorionicity and preterm birth in twin pregnancies: A systematic review involving 29,864 twin pregnancies

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Association between chorionicity and preterm birth in twin pregnancies : A systematic review involving 29,864 twin pregnancies. / Marleen, Shemoon; Dias, Chamalika; Nandasena, Ruvini; MacGregor, Rebecca; Allotey, John; Aquilina, Joseph; Khalil, Asma; Thangaratinam, Shakila.

In: BJOG: An International Journal of Obstetrics & Gynaecology, 05.09.2020.

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Marleen, Shemoon ; Dias, Chamalika ; Nandasena, Ruvini ; MacGregor, Rebecca ; Allotey, John ; Aquilina, Joseph ; Khalil, Asma ; Thangaratinam, Shakila. / Association between chorionicity and preterm birth in twin pregnancies : A systematic review involving 29,864 twin pregnancies. In: BJOG: An International Journal of Obstetrics & Gynaecology. 2020.

Bibtex

@article{9004f67d25a346a587690cd298a72918,
title = "Association between chorionicity and preterm birth in twin pregnancies: A systematic review involving 29,864 twin pregnancies",
abstract = "BACKGROUND: The perinatal mortality and morbidity among twins vary by chorionicity. Although it is considered that monochorionicity is associated with an increased risk of preterm birth in twin pregnancies, no systematic review exists evaluating this association.OBJECTIVE: This systematic review was undertaken to assess the association between preterm birth and chorionicity in twin pregnancies.SEARCH STRATEGY: We searched the electronic databases from January 1990 to July 2019 without language restrictions.SELECTION CRITERIA: All studies on twin pregnancies where chorionicity and preterm birth were evaluated were included.DATA COLLECTION AND ANALYSIS: Findings are reported as odds ratios with 95% confidence intervals. The estimates are pooled using random-effects meta-analysis.MAIN RESULTS: From 13,156 citations, we included 39 studies (29,864 pregnancies). Monochorionicity was significantly associated with increased risk of preterm birth at ≤28, ≤32, ≤34 and <37 weeks in women asymptomatic and symptomatic for preterm labour. (OR 2.14, 95% CI 1.52-3.02 I2 =46%, OR 1.55, 95% CI 1.27-1.89 I2 =68%, OR 1.47, 95% CI 1.27-1.69, I2 =60%, OR 1.66, 95% CI 1.43-1.93, I2 =65%). Among those asymptomatic for preterm labour, significantly increased odds of preterm birth was seen for monochorionicity at gestations ≤34 weeks (OR 1.85, 95% CI 1.42-2.40, I2 =25%) and <37 weeks (OR 1.75, 95% CI 1.22-2.53, I2 =61%). Sensitivity analysis showed significantly increased odds of spontaneous preterm birth at ≤34 weeks and <37 weeks for monochorionicity. (OR 1.25, 95% CI 1.01-1.55, I2 =0% and OR 1.41, 95% CI 1.13-1.78, I2 =0%).CONCLUSION: Monochorionicity is significantly associated with preterm birth at all gestations.",
author = "Shemoon Marleen and Chamalika Dias and Ruvini Nandasena and Rebecca MacGregor and John Allotey and Joseph Aquilina and Asma Khalil and Shakila Thangaratinam",
note = "This article is protected by copyright. All rights reserved.",
year = "2020",
month = sep,
day = "5",
doi = "10.1111/1471-0528.16479",
language = "English",
journal = "BJOG: An International Journal of Obstetrics & Gynaecology",
issn = "1470-0328",
publisher = "Wiley",

}

RIS

TY - JOUR

T1 - Association between chorionicity and preterm birth in twin pregnancies

T2 - A systematic review involving 29,864 twin pregnancies

AU - Marleen, Shemoon

AU - Dias, Chamalika

AU - Nandasena, Ruvini

AU - MacGregor, Rebecca

AU - Allotey, John

AU - Aquilina, Joseph

AU - Khalil, Asma

AU - Thangaratinam, Shakila

N1 - This article is protected by copyright. All rights reserved.

PY - 2020/9/5

Y1 - 2020/9/5

N2 - BACKGROUND: The perinatal mortality and morbidity among twins vary by chorionicity. Although it is considered that monochorionicity is associated with an increased risk of preterm birth in twin pregnancies, no systematic review exists evaluating this association.OBJECTIVE: This systematic review was undertaken to assess the association between preterm birth and chorionicity in twin pregnancies.SEARCH STRATEGY: We searched the electronic databases from January 1990 to July 2019 without language restrictions.SELECTION CRITERIA: All studies on twin pregnancies where chorionicity and preterm birth were evaluated were included.DATA COLLECTION AND ANALYSIS: Findings are reported as odds ratios with 95% confidence intervals. The estimates are pooled using random-effects meta-analysis.MAIN RESULTS: From 13,156 citations, we included 39 studies (29,864 pregnancies). Monochorionicity was significantly associated with increased risk of preterm birth at ≤28, ≤32, ≤34 and <37 weeks in women asymptomatic and symptomatic for preterm labour. (OR 2.14, 95% CI 1.52-3.02 I2 =46%, OR 1.55, 95% CI 1.27-1.89 I2 =68%, OR 1.47, 95% CI 1.27-1.69, I2 =60%, OR 1.66, 95% CI 1.43-1.93, I2 =65%). Among those asymptomatic for preterm labour, significantly increased odds of preterm birth was seen for monochorionicity at gestations ≤34 weeks (OR 1.85, 95% CI 1.42-2.40, I2 =25%) and <37 weeks (OR 1.75, 95% CI 1.22-2.53, I2 =61%). Sensitivity analysis showed significantly increased odds of spontaneous preterm birth at ≤34 weeks and <37 weeks for monochorionicity. (OR 1.25, 95% CI 1.01-1.55, I2 =0% and OR 1.41, 95% CI 1.13-1.78, I2 =0%).CONCLUSION: Monochorionicity is significantly associated with preterm birth at all gestations.

AB - BACKGROUND: The perinatal mortality and morbidity among twins vary by chorionicity. Although it is considered that monochorionicity is associated with an increased risk of preterm birth in twin pregnancies, no systematic review exists evaluating this association.OBJECTIVE: This systematic review was undertaken to assess the association between preterm birth and chorionicity in twin pregnancies.SEARCH STRATEGY: We searched the electronic databases from January 1990 to July 2019 without language restrictions.SELECTION CRITERIA: All studies on twin pregnancies where chorionicity and preterm birth were evaluated were included.DATA COLLECTION AND ANALYSIS: Findings are reported as odds ratios with 95% confidence intervals. The estimates are pooled using random-effects meta-analysis.MAIN RESULTS: From 13,156 citations, we included 39 studies (29,864 pregnancies). Monochorionicity was significantly associated with increased risk of preterm birth at ≤28, ≤32, ≤34 and <37 weeks in women asymptomatic and symptomatic for preterm labour. (OR 2.14, 95% CI 1.52-3.02 I2 =46%, OR 1.55, 95% CI 1.27-1.89 I2 =68%, OR 1.47, 95% CI 1.27-1.69, I2 =60%, OR 1.66, 95% CI 1.43-1.93, I2 =65%). Among those asymptomatic for preterm labour, significantly increased odds of preterm birth was seen for monochorionicity at gestations ≤34 weeks (OR 1.85, 95% CI 1.42-2.40, I2 =25%) and <37 weeks (OR 1.75, 95% CI 1.22-2.53, I2 =61%). Sensitivity analysis showed significantly increased odds of spontaneous preterm birth at ≤34 weeks and <37 weeks for monochorionicity. (OR 1.25, 95% CI 1.01-1.55, I2 =0% and OR 1.41, 95% CI 1.13-1.78, I2 =0%).CONCLUSION: Monochorionicity is significantly associated with preterm birth at all gestations.

U2 - 10.1111/1471-0528.16479

DO - 10.1111/1471-0528.16479

M3 - Review article

C2 - 32888235

JO - BJOG: An International Journal of Obstetrics & Gynaecology

JF - BJOG: An International Journal of Obstetrics & Gynaecology

SN - 1470-0328

ER -