Arterial stiffness in chronic kidney disease: causes and consequences.

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Arterial stiffness in chronic kidney disease: causes and consequences. / Chue, Colin; Townend, Jonathan; Steeds, Richard; Ferro, Charles.

In: Heart, Vol. 96, No. 11, 01.06.2010, p. 817-23.

Research output: Contribution to journalReview article

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Chue, Colin ; Townend, Jonathan ; Steeds, Richard ; Ferro, Charles. / Arterial stiffness in chronic kidney disease: causes and consequences. In: Heart. 2010 ; Vol. 96, No. 11. pp. 817-23.

Bibtex

@article{0de503a37e51487ba7debf6d71ace63b,
title = "Arterial stiffness in chronic kidney disease: causes and consequences.",
abstract = "Chronic kidney disease is associated with elevated cardiovascular risk, and heart failure and arrhythmias are the biggest causes of cardiovascular death in this population. Increased arterial stiffness is a hallmark of chronic kidney disease and is associated with adverse alterations in cardiac structure and function that may predispose to an increased risk of cardiovascular death. These changes are already apparent in early kidney disease, which is highly prevalent in the developed world. The mechanisms underlying increased arterial stiffness in chronic kidney disease are undoubtedly complex, but an understanding is paramount to enable the development of novel therapeutic strategies to prevent or reverse this pathophysiology and therefore reduce the cardiovascular disease burden in this high-risk cohort.",
author = "Colin Chue and Jonathan Townend and Richard Steeds and Charles Ferro",
year = "2010",
month = jun,
day = "1",
doi = "10.1136/hrt.2009.184879",
language = "English",
volume = "96",
pages = "817--23",
journal = "Heart",
issn = "1355-6037",
publisher = "BMJ Publishing Group",
number = "11",

}

RIS

TY - JOUR

T1 - Arterial stiffness in chronic kidney disease: causes and consequences.

AU - Chue, Colin

AU - Townend, Jonathan

AU - Steeds, Richard

AU - Ferro, Charles

PY - 2010/6/1

Y1 - 2010/6/1

N2 - Chronic kidney disease is associated with elevated cardiovascular risk, and heart failure and arrhythmias are the biggest causes of cardiovascular death in this population. Increased arterial stiffness is a hallmark of chronic kidney disease and is associated with adverse alterations in cardiac structure and function that may predispose to an increased risk of cardiovascular death. These changes are already apparent in early kidney disease, which is highly prevalent in the developed world. The mechanisms underlying increased arterial stiffness in chronic kidney disease are undoubtedly complex, but an understanding is paramount to enable the development of novel therapeutic strategies to prevent or reverse this pathophysiology and therefore reduce the cardiovascular disease burden in this high-risk cohort.

AB - Chronic kidney disease is associated with elevated cardiovascular risk, and heart failure and arrhythmias are the biggest causes of cardiovascular death in this population. Increased arterial stiffness is a hallmark of chronic kidney disease and is associated with adverse alterations in cardiac structure and function that may predispose to an increased risk of cardiovascular death. These changes are already apparent in early kidney disease, which is highly prevalent in the developed world. The mechanisms underlying increased arterial stiffness in chronic kidney disease are undoubtedly complex, but an understanding is paramount to enable the development of novel therapeutic strategies to prevent or reverse this pathophysiology and therefore reduce the cardiovascular disease burden in this high-risk cohort.

U2 - 10.1136/hrt.2009.184879

DO - 10.1136/hrt.2009.184879

M3 - Review article

C2 - 20406771

VL - 96

SP - 817

EP - 823

JO - Heart

JF - Heart

SN - 1355-6037

IS - 11

ER -